Evidence mapPaperPMID 31290436Full record

ReviewNeural regeneration research2019

Diabetic neuropathy research: from mouse models to targets for treatment.

Vuong M Pham, Shinji Matsumura, Tayo Katano, Nobuo Funatsu, Seiji Ito

Abstract readReview
In one paragraph

Review in Neural regeneration research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. International journal of molecular sciences · 2025
    Article
  7. Article
  8. Ameliorating Effect of Red Fruit (Journal of pharmacopuncture · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Advances in Mechanism Research onFrontiers in pharmacology · 2022
    Review
  19. Effects of Melatonin on Diabetic Neuropathy and Retinopathy.International journal of molecular sciences · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vuong M PhamDepartment of Medical Chemistry, Kansai Medical University, Hirakata, Osaka, Japan; Singapore Institute for Neurotechnology (SINAPSE), National University of Singapore, Singapore.
Shinji MatsumuraDepartment of Medical Chemistry, Kansai Medical University, Hirakata, Osaka, Japan.
Tayo KatanoDepartment of Medical Chemistry, Kansai Medical University, Hirakata, Osaka, Japan.
Nobuo FunatsuDepartment of Medical Chemistry, Kansai Medical University, Hirakata, Osaka, Japan.
Seiji ItoDepartment of Medical Chemistry, Kansai Medical University, Hirakata; Department of Anesthesiology, Osaka Medical College, Takatsuki, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic neuropathy is one of the most serious complications of diabetes, and its increase shows no sign of stopping. Furthermore, current clinical treatments do not yet approach the best effectiveness. Thus, the development of better strategies for treating diabetic neuropathy is an urgent matter. In this review, we first discuss the advantages and disadvantages of some major mouse models of diabetic neuropathy and then address the targets for mechanism-based treatment that have been studied. We also introduce our studies on each part. Using stem cells as a source of neurotrophic factors to target extrinsic factors of diabetic neuropathy, we found that they present a promising treatment.

Indexed as

brain derived neurotrophic factordiabetesextrinsic factorsnerve growth factornerve regenerationneurotrophic factorsnon-obese type 2 diabetesphosphatase and tensin homologstem cellstreptozotocin

Identifiers

PMID31290436
PMCPMC6676867

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.