Evidence map›Paper›PMID 31293321›Full record

ArticleJournal of human reproductive sciences

Genetics of Female Infertility: Molecular Study of Newborn Ovary Homeobox Gene in Poor Ovarian Responders.

Osamah Batiha, Nour Alhoda Alahmad, Amer Sindiani, Khaldon Bodoor, Sherin Shaaban, Mohammad Al-Smadi

Open access · diamondAbstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Review
  3. Review
  4. Association between polymorphisms inFrontiers in veterinary science · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Osamah BatihaDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Nour Alhoda AlahmadDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Amer SindianiDepartment of Obstetrics and Gynecology, Jordan University of Science and Technology, Irbid, Jordan.
Khaldon BodoorDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Sherin ShaabanDepartment of Applied Biological Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Mohammad Al-SmadiDepartment of Reproductive Endocrinology and IVF Unit, King Hussein Medical Center, Amman, Jordan.
Jordan University of Science and Technology · JOKing Hussein Medical Center · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNewborn ovary homeobox (

aimsThe aim of the study is to investigate the association between seven known SETTINGS AND

designThis was a case-control study of 60 females with POR for controlled ovarian hyperstimulation and 59 healthy females with no history of reproductive problems. Blood samples were collected from the participants and seven SNPs of SUBJECTS AND

methodsDNA was extracted from blood samples. Polymerase chain reaction with primers specific for seven known SNPs in

resultsThe seven SNPs investigated in this study, namely, rs77587352 (c.271G>T, p. Gly91Trp), rs7800847 (c.349C>T, p. Arg117Trp), rs193303102 (c.907C>T, p. Arg303X), rs193303103 (c.1025G>C, p. Ser342Thr), rs193303104 (c.1048G>T, p. Val350Leu), rs201947677 (c.1064G>A, p. Arg355His), and rs146227301 (c.1856C>T, p. Pro619Leu), only represent the wild-type allele in both females with POR and healthy participants.

conclusionsThe results show that only monomorphic genotype of the

Indexed as

Female infertilitynewborn ovary homeobox genepoor ovarian response

Identifiers

PMID31293321
PMCPMC6594122
OpenAlexW2949410016

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.