Evidence map›Paper›PMID 31295897›Full record

ReviewNutrients2019

Postprandial Glucose Control in Type 1 Diabetes: Importance of the Gastric Emptying Rate.

Roberta Lupoli, Federica Pisano, Brunella Capaldo

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07278063 (Effect of Gender and Meal Composition on the Postprandial Glycemic Response in People With Type 1 Diabetes), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07278063 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Gender and Meal Composition on the Postprandial Glycemic Response in People With Type 1 Diabetes: Impact of Fat Content and Menstrual Cycle Phases

TypeinterventionalSponsorInstituto de Investigacion Sanitaria La FeRan2026 to 2028Enrolled50ConditionsType 1 Diabetes Mellitus, Glycemic Variability, Sex Characteristics, Menstrual CycleArmsLow Fat Mixed Meal, High Fat Mixed Meal
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Roberta LupoliDepartment of Molecular Medicine and Medical Biotechnology, Federico II University, 80131 Naples, Italy.
Federica PisanoDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.
Brunella CapaldoDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy. bcapaldo@unina.it.ORCID 0000-0001-5222-1524
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The achievement of optimal post-prandial (PP) glucose control in patients with type 1 diabetes (T1DM) remains a great challenge. This review summarizes the main factors contributing to PP glucose response and discusses the likely reasons why PP glucose control is rarely achieved in T1DM patients. The macronutrient composition of the meal, the rate of gastric emptying and premeal insulin administration are key factors affecting the PP glucose response in T1DM. Although the use of continuous insulin infusion systems has improved PP glucose control compared to conventional insulin therapy, there is still need for further ameliorations. T1DM patients frequently present a delayed gastric emptying (GE) that produces a lower but more prolonged PP hyperglycemia. In addition, delayed GE is associated with a longer time to reach the glycemic peak, with a consequent mismatch between PP glucose elevation and the timing of premeal insulin action. On this basis, including GE time and meal composition in the algorithms for insulin bolus calculation of the insulin delivery systems could be an important step forward for optimization of PP glucose control in T1DM.

Indexed as

Diabetes Mellitus, Type 1Blood GlucoseGastric EmptyingHumansInsulinMealsPostprandial PeriodBlood GlucoseInsulingastric emptyingmealpostprandial glucosepremeal insulin

Identifiers

PMID31295897
PMCPMC6683017
OpenAlexW2961418016

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.