Evidence map›Paper›PMID 31297068›Full record

ArticleFrontiers in physiology2019

The Many Faces of

Micaela Lasser, Benjamin Pratt, Connor Monahan, Seung Woo Kim, Laura Anne Lowery

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. The neurodevelopmental disorder risk geneDevelopment (Cambridge, England) · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Micaela LasserDepartment of Biology, Boston College, Chestnut Hill, MA, United States.
Benjamin PrattDepartment of Biology, Boston College, Chestnut Hill, MA, United States.
Connor MonahanDepartment of Biology, Boston College, Chestnut Hill, MA, United States.
Seung Woo KimDepartment of Biology, Boston College, Chestnut Hill, MA, United States.
Laura Anne LoweryDepartment of Biology, Boston College, Chestnut Hill, MA, United States.
Boston College · US

Funding

Genomic basis of phenotypic variability of genomic disordersR01GM121907 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI GIRIRAJAN, SANTHOSH · 2017 to 2025
$5.2M
Elucidating mechanistic connections between guidance signaling, microtubule regulation, and growth cone steering: Diversity SupplementR01MH109651 · NIMH · BOSTON MEDICAL CENTER · PI Laura Anne LOWERY · 2016 to 2026
$4.3M
Role of TACC3 in Cranial Neural Crest Cell Migration:Implications for Craniofacial DisordersR03DE025824 · NIDCR · BOSTON COLLEGE · PI LOWERY, LAURA ANNE · 2016 to 2017
$235k
NIDCR NIH HHS R03 DE025824NIGMS NIH HHS R01 GM121907NIMH NIH HHS R01 MH109651
6 · The paper itself

Abstract

Wolf-Hirschhorn syndrome (WHS) is a rare developmental disorder characterized by intellectual disability and various physical malformations including craniofacial, skeletal, and cardiac defects. These phenotypes, as they involve structures that are derived from the cranial neural crest, suggest that WHS may be associated with abnormalities in neural crest cell (NCC) migration. This syndrome is linked with assorted mutations on the short arm of chromosome 4, most notably the microdeletion of a critical genomic region containing several candidate genes. However, the function of these genes during embryonic development, as well as the cellular and molecular mechanisms underlying the disorder, are still unknown. The model organism

Indexed as

craniofacialdevelopmentneural crest cellsWolf–Hirschhorn syndromeXenopus

Identifiers

PMID31297068
PMCPMC6607408
OpenAlexW2949745556

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.