Evidence map›Paper›PMID 31311884›Full record

ArticlemBio2019

Clinical Persistence of Chlamydia trachomatis Sexually Transmitted Strains Involves Novel Mutations in the Functional αββα Tetramer of the Tryptophan Synthase Operon.

Naraporn Somboonna, Noa Ziklo, Thomas E Ferrin, Jung Hyuk Suh, Deborah Dean

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Coordinated topoisomerase function shapes the fluoroquinolone response ofbioRxiv : the preprint server for biology · 2026
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  3. Anti-International journal of molecular sciences · 2026
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  6. Requirement of GrgA forbioRxiv : the preprint server for biology · 2023
    Article
  7. Review
  8. Article
  9. Genome organization and genomics inFrontiers in cellular and infection microbiology · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Transcriptional Landscape ofMicroorganisms · 2020
    Article
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Naraporn Somboonna *Center for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA.
Noa Ziklo *Center for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA.
Thomas E FerrinDepartment of Pharmaceutical Chemistry, University of California, San Francisco, California, USA.
Jung Hyuk SuhCenter for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA.
Deborah DeanCenter for Immunobiology and Vaccine Development, University of California San Francisco Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA ddean@chori.org.
University of California, San Francisco · USUCSF Benioff Children's Hospital · US

Funding

Multiplex diagnostic for biothreat C. psittaci & non-threat respiratory pathogensR01AI098843 · NIAID · CHILDREN'S HOSPITAL & RES CTR AT OAKLAND · PI DEAN, DEBORAH ANNE, READ, TIMOTHY D. · 2012 to 2016
$5.5M
C. trachomatis genomics, strain typing, and evolutionR01AI059647 · NIAID · CHILDREN'S HOSPITAL &RES CTR AT OAKLAND · PI DEAN, DEBORAH ANNE · 2004 to 2008
$2.8M
NIAID NIH HHS R01 AI059647NIAID NIH HHS R01 AI098843
6 · The paper itself

Abstract

Clinical persistence of

Indexed as

MutationOperonAmino Acid SequenceBase SequenceChlamydia InfectionsChlamydia trachomatisFrameshift MutationGene Expression Regulation, BacterialHumansModels, MolecularPhylogenyProtein ConformationSequence DeletionSexually Transmitted Diseases, BacterialTryptophan SynthaseTryptophan SynthaseChlamydia trachomatisindoleinterferon gammasexually transmitted infectionstrpAtryptophan synthesis

Identifiers

PMID31311884
PMCPMC6635532
OpenAlexW2958146825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.