Evidence map›Paper›PMID 31316396›Full record

ArticleFrontiers in physiology2019

Geometrical Patterning and Constituent Cell Heterogeneity Facilitate Electrical Conduction Disturbances in a Human Induced Pluripotent Stem Cell-Based Platform: An

Hiroyuki Nakanishi, Jong-Kook Lee, Keiko Miwa, Kiyoshi Masuyama, Hideki Yasutake, Jun Li, Satoki Tomoyama, Yayoi Honda, Jiro Deguchi, Shinji Tsujimoto and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Towards Improved HumanBiomedicines · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. MulticellularFrontiers in cardiovascular medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Hiroyuki NakanishiDepartment of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Jong-Kook LeeDepartment of Advanced Cardiovascular Regenerative Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Keiko MiwaDepartment of Mechanical Engineering, Kyushu University, Fukuoka, Japan.
Kiyoshi MasuyamaDepartment of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Hideki YasutakeDepartment of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Jun LiDepartment of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Satoki TomoyamaDepartment of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Yayoi HondaPreclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan.
Jiro DeguchiPreclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan.
Shinji TsujimotoRegenerative & Cellular Medicine Office, Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan.
Kyoko HidakaDepartment of Advanced Cardiovascular Regenerative Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Shigeru MiyagawaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Yoshiki SawaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Issei KomuroDepartment of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yasushi SakataDepartment of Cardiovascular Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.
Osaka University · JPSumitomo Dainippon Pharma (Japan) · JPKyushu University · JPThe University of Kitakyushu · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic foci from pulmonary veins (PVs) comprise the main trigger associated with the initiation of atrial fibrillation (AF). An abrupt anatomical narrow-to-wide transition, modeled as

Indexed as

atrial-like cardiomyocytesconstituent cell heterogeneityelectrical conductiongeometrical patterninghuman atrial fibroblastshuman induced pluripotent stem cellsimpaired conductionsource-to-sink mismatch

Identifiers

PMID31316396
PMCPMC6610482
OpenAlexW2954236787

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.