Evidence map›Paper›PMID 31319935›Full record

ArticleBiological psychiatry2019

Targeting the Interaction Between Apolipoprotein E and Amyloid Precursor Protein: A Novel Alzheimer's Disease Therapy.

Huntington Potter, Heidi J Chial

Abstract readComment
PubMed Publisher
In one paragraph

Article in Biological psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Iron-responsive-like elements and neurodegenerative ferroptosis.Learning & memory (Cold Spring Harbor, N.Y.) · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Huntington PotterDepartment of Neurology, Rocky Mountain Alzheimer's Disease Center, and the Linda Crnic Institute for Down Syndrome, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: huntington.potter@ucdenver.edu.
Heidi J ChialDepartment of Neurology, Rocky Mountain Alzheimer's Disease Center, and the Linda Crnic Institute for Down Syndrome, University of Colorado School of Medicine, Aurora, Colorado.
Rocky Mountain MS Center · US

Funding

Neuronal dysfunction caused by Abeta inhibition of MT motorsR01NS076291 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI POTTER, HUNTINGTON · 2011 to 2015
$1.6M
Abnormal Low Density Lipoprotein Receptor Localization and Function in ADR01AG037942 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI POTTER, HUNTINGTON · 2011 to 2015
$1.5M
NIA NIH HHS R01 AG037942NINDS NIH HHS R01 NS076291
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAmyloid beta-Protein PrecursorApolipoproteins ECognitionHumansAmyloid beta-Protein PrecursorApolipoproteins E

Identifiers

PMID31319935
OpenAlexW2961943314

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.