Evidence map›Paper›PMID 31330833›Full record

ArticleCancers2019

Giorgia Marisi, Elisabetta Petracci, Francesco Raimondi, Luca Faloppi, Francesco Giuseppe Foschi, Gianfranco Lauletta, Massimo Iavarone, Matteo Canale, Martina Valgiusti, Luca Maria Neri and 11 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05291338 (Pharmacogenetic Study in Hepatocellular Carcinoma Patients Underwent TACE), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05291338 completednot on this mapstarted 2022, after this paper: background citation

Pharmacogenetic Study in Hepatocellular Carcinoma Patients Underwent TACE

TypeobservationalSponsorRehab WeridaRan2022 to 2023Enrolled107ConditionsHepatocellular CarcinomaArmsDoxorubicin, Lipiodol
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Role of Genetic Variations in the Hepatic Handling of Drugs.International journal of molecular sciences · 2020 · on this map
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 2 countries.

Giorgia MarisiBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy. giorgia.marisi@irst.emr.it.
Elisabetta PetracciUnit of Biostatistics and Clinical Trials, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy.
Francesco RaimondiCellNetworks-Cluster of Excellence (EXC81) and Biochemistry Center (BZH), Heidelberg University, 69120 Heidelberg, Germany.
Luca FaloppiDepartment of Medical Oncology, University Hospital Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-3689-3085
Francesco Giuseppe FoschiDPT Internal Medicine, Faenza Hospital, AUSL Romagna, 48018 Faenza, Italy.
Gianfranco LaulettaDepartment of Biomedical Sciences and Human Oncology, Internal Medicine "G. Baccelli", University of Bari "A. Moro", 70121 Bari, Italy.
Massimo Iavarone"A.M.&A. Migliavacca" Center for Liver Disease, 1st Division of Gastroenterology, Fondazione IRCCS Ca' Granda Maggiore Hospital, University of Milan, 20122 Milan, Italy.
Matteo CanaleBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy.ORCID 0000-0002-9768-7149
Martina ValgiustiDepartment of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy.
Luca Maria NeriDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy.
Paola UliviBiosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy.
Giulia OrsiDivision of Oncology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Giulia RovestiDivision of Oncology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Ranka VukoticDepartment of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Fabio ContiDPT Internal Medicine, Faenza Hospital, AUSL Romagna, 48018 Faenza, Italy.
Alessandro CucchettiGeneral and Oncology Surgery, Morgagni-Pierantoni Hospital, 47121 Forli, Italy.
Giorgio ErcolaniGeneral and Oncology Surgery, Morgagni-Pierantoni Hospital, 47121 Forli, Italy.
Kalliopi AndrikouDivision of Oncology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Stefano CascinuDivision of Oncology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.
Mario ScartozziDepartment of Medical Oncology, University Hospital Cagliari, 09124 Cagliari, Italy.
Andrea Casadei-GardiniDivision of Oncology, Department of Medical and Surgical Sciences for Children & Adults, University-Hospital of Modena and Reggio Emilia, 41121 Modena, Italy.ORCID 0000-0001-6289-7202
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITUniversity of Modena and Reggio Emilia · ITOspedale G.B. Morgagni - L.Pierantoni · ITOspedale per gli Infermi · ITUniversity of Cagliari · ITHeidelberg University · DEUniversity of Bari Aldo Moro · ITUniversity of Bologna · ITUniversity of Ferrara · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sorafenib represents the standard of care for advanced hepatocellular carcinoma (HCC), even though a large number of patients have reported limited efficacy. The aim of the present study was to evaluate the prognostic value of single-nucleotide polymorphisms on angiopoietin-2 (

Indexed as

angiogenesisangiopoietinbiomarkersChild–Pughendothelial nitric oxide synthasehepatocellular carcinomasingle-nucleotide polymorphismVEGF

Identifiers

PMID31330833
PMCPMC6679015
OpenAlexW2963055920

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.