ReviewNutrients2019
Weight Loss and Hypertension in Obese Subjects.
Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Italian guidelines for the management of adult individuals with overweight and obesity and metabolic comorbidities that are resistant to behavioral treatment.Journal of endocrinological investigation · 2024Guideline
- Pooled it
- Key Predictors of Relevant Weight Loss in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease.United European gastroenterology journal · 2025Article
- Esophagectomy enhances hypertension remission and metabolism via weight loss in esophageal Cancer patients with hypertension.Scientific reports · 2025Article
- Obesity-Related Disorders in Türkiye: A Multi Center, Retrospective, Cross-Sectional Analysis from the OBREDI-TR Study.Journal of clinical medicine · 2025Article
- Does a high body mass index remain a protective factor in hip fracture patients with hypertension and diabetes?Aging clinical and experimental research · 2025Article
- Mechanisms and treatment of obesity-related hypertension-Part 2: Treatments.Clinical kidney journal · 2025Review
- Overweight-Related Hypertension in Middle-Aged Men Is Linked to Elevated Leptin, TNF-α, IL-6, Cholesterol, and Reduced Testosterone.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Article
- Exploring the potential association between serum selenium and hypertension in obese adult males in the United States.Scientific reports · 2025Article
- Longitudinal blood pressure and body mass index in South African adolescents.Frontiers in pediatrics · 2025Article
- Exploring the Sociodemographic, Clinical, and Lifestyle Determinants of Hypertension Among Sedentary Workers: A Cross-Sectional Study in the Cape Coast Metropolis.BioMed research international · 2025Article
- The Role of Lifestyle Modifications in Preventing and Managing Systemic Hypertension: Current Guidelines and Future Directions.Annals of African medicine · 2025Article
- Serum Vitamin D Level Correlates Significantly With Leptin and Tumor Necrosis Factor-Alpha in Overweight Postmenopausal Women With Hypertension.Journal of clinical medicine research · 2025Article
- Weight Loss Therapies and Hypertension Benefits.Biomedicines · 2024Review
- GLP-1-based therapies for the treatment of resistant hypertension in individuals with overweight or obesity: a review.EClinicalMedicine · 2024Review
- ACTION-FRANCE: Insights into Perceptions, Attitudes, and Barriers to Obesity Management in France.Journal of clinical medicine · 2024Article
- Article
- Positive correlation between body weight and body mass index with blood pressure in young adults.Narra J · 2024Article
- Clinical effectiveness and cost-impact after 2 years of a ketogenic diet and virtual coaching intervention for patients with diabetes.Diabetes, obesity & metabolism · 2024Article
- Delay Discounting and BMI in Hypertensives: Serial Mediations of Self-Efficacy, Physical Activity and Sedentary Behavior.Journal of multidisciplinary healthcare · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial hypertension is strongly related to overweight and obesity. In obese subjects, several mechanisms may lead to hypertension such as insulin and leptin resistance, perivascular adipose tissue dysfunction, renal impairment, renin-angiotensin-aldosterone-system activation and sympathetic nervous system activity. Weight loss (WL) seems to have positive effects on blood pressure (BP). The aim of this review was to explain the mechanisms linking obesity and hypertension and to evaluate the main studies assessing the effect of WL on BP. We analysed studies published in the last 10 years (13 studies either interventional or observational) showing the effect of WL on BP. Different WL strategies were taken into account-diet and lifestyle modification, pharmacological intervention and bariatric surgery. Although a positive effect of WL could be identified in each study, the main difference seems to be the magnitude and the durability of BP reduction over time. Nevertheless, further follow-up data are needed: there is still a lack of evidence about long term effects of WL on hypertension. Hence, given the significant results obtained in several recent studies, weight management should always be pursued in obese patients with hypertension.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.