Evidence map›Paper›PMID 31332663›Full record

ReviewHeart failure reviews2020

Myocardial ischemia and coronary disease in heart failure.

Beniamino R Pagliaro, Francesco Cannata, Giulio G Stefanini, Leonardo Bolognese

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 1 synthesis or guideline pooled it, 231 citations in OpenAlex.

  1. Pooled it
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  17. Review
  18. The effect of TIM1Cell death discovery · 2025
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  20. Review

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Beniamino R PagliaroCardio Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy.
Francesco CannataCardio Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy.
Giulio G StefaniniCardio Center, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. giulio.stefanini@hunimed.eu.ORCID http://orcid.org/0000-0002-3558-6967
Leonardo BologneseDipartimento Cardio Neuro Vascolare, Ospedale San Donato, Arezzo, Italy.
Humanitas University · ITOspedale San Donato · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure is a complex clinical syndrome and represents the final path of numerous heart diseases. Coronary artery disease is recognized as the primary risk factor for heart failure development, being the main etiological factor in more than 50% of heart failure patients in North America and Europe. Regardless of overt coronary artery disease, myocardial ischemia is a common finding in failing hearts, likely due to structural or functional coronary circulation alterations. Ischemia is a self-propagating process which irreversibly impairs the cardiac function and negatively impacts prognosis. Thus, a better and thorough understanding of myocardial ischemia pathophysiology in heart failure would likely lead to significantly improved outcomes in these patients. This review aims to describe the mechanisms of myocardial ischemia and coronary artery disease in heart failure, focusing on coronary circulation dysfunctions due to increased parietal stress or non-obstructive coronary disease, and discussing the association and management of coronary artery disease in patients with heart failure.

Indexed as

Coronary Artery DiseaseCoronary CirculationCoronary VesselsDisease ProgressionHeart FailureHumansMyocardial IschemiaRandomized Controlled Trials as TopicRisk FactorsCoronary artery diseaseHeart failureMicrovascular dysfunctionMyocardial ischemiaWall stress

Identifiers

PMID31332663
OpenAlexW2963126389

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.