Evidence map›Paper›PMID 31333965›Full record

ArticlePlastic and reconstructive surgery. Global open2019

An Update on Measures of Preoperative Glycemic Control.

Ledibabari M Ngaage, Emmanuel N Osadebey, Sebastian T E Tullie, Adekunle Elegbede, Erin M Rada, Elias K Spanakis, Nelson Goldberg, Sheri Slezak, Yvonne M Rasko

Registry-linked trialAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03508934 (Continuous Glucose Monitoring in Insulin Treated Hospitalized Veterans With DM2 at Higher Risk for Hypoglycemia), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03508934 naactive not recruitingnot on this map

Continuous Glucose Monitoring in Insulin Treated Hospitalized Veterans With DM2 at Higher Risk for Hypoglycemia

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2018 to 2026Enrolled218ConditionsDiabetes Mellitus, Type 2, HypoglycemiaArmsGTS (Continuous Glucose Monitoring), POC (Point of Care)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ledibabari M NgaageDivision of Plastic Surgery, University of Maryland School of Medicine, Baltimore, Md.
Emmanuel N OsadebeyDepartment of Orthopaedic Surgery, Howard University Hospital, Wash.
Sebastian T E TullieEast Kent NHS Foundation Trust, South Thames Foundation School, London, United Kingdom.
Adekunle ElegbedeDepartment of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, University of Maryland Medical Center, Baltimore, Md.
Erin M RadaDivision of Plastic Surgery, University of Maryland School of Medicine, Baltimore, Md.
Elias K SpanakisDivision of Diabetes and Endocrinology, Baltimore Veterans Affairs Medical Center, Baltimore, Md.
Nelson GoldbergDivision of Plastic Surgery, University of Maryland School of Medicine, Baltimore, Md.
Sheri SlezakDivision of Plastic Surgery, University of Maryland School of Medicine, Baltimore, Md.
Yvonne M RaskoDivision of Plastic Surgery, University of Maryland School of Medicine, Baltimore, Md.

Funding

Continuous Glucose Monitoring in Insulin Treated Hospitalized Veterans with DM2 at Higher Risk for HypoglycemiaI01CX001825 · VA · BALTIMORE VA MEDICAL CENTER · PI SPANAKIS, ILIAS · 2018 to 2023
–
CSRD VA I01 CX001825
6 · The paper itself

Abstract

Glycemic control represents a modifiable preoperative risk factor in surgery. Traditionally, hemoglobin A1c (HbA1c) and plasma glucose are utilized as measures of glycemic control. However, studies show mixed results regarding the ability of these conventional measures to predict adverse surgical outcomes. This may be explained by the time window captured by HbA1c and serum glucose: long-term and immediate glycemic control, respectively. Fructosamine, glycosylated albumin, and 1,5-anhydroglucitol constitute alternative metrics of glycemic control that are of growing interest but are underutilized in the field of surgery. These nontraditional measures reflect the temporal variations in glycemia over the preceding days to weeks. Therefore, they may more accurately reflect glycemic control within the time window that most significantly affects surgical outcomes. Additionally, these alternative measures are predictive of negative outcomes, even in the nondiabetic population and in patients with chronic renal disease and anemia, for whom HbA1c performs poorly. Adopting these newer metrics of glycemia may enhance the value of preoperative evaluation, such that the effectiveness of any preoperative glycemic control interventions can be assessed, and adverse outcomes associated with hyperglycemia better predicted. The goal of this review is to provide an update on the preoperative management of glycemia and to describe alternative metrics that may improve our ability to predict and control for the negative outcomes associated with poor glycemic control.

Identifiers

PMID31333965
PMCPMC6571350

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.