Evidence map›Paper›PMID 31335759›Full record

Trial reportTransplantation2020

Impact of a Mobile Health Intervention on Long-term Nonadherence After Lung Transplantation: Follow-up After a Randomized Controlled Trial.

Emily M Geramita, Annette J DeVito Dabbs, Andrea F DiMartini, Joseph M Pilewski, Galen E Switzer, Donna M Posluszny, Larissa Myaskovsky, Mary Amanda Dew

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00818025 (Phase III Trial of Pocket PATH), which is not on this map. Cited by 27 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 7 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00818025 nacompletednot on this map

Phase III Trial of Pocket PATH: A Computerized Intervention to Promote Self-Care

TypeinterventionalSponsorUniversity of PittsburghRan2009 to 2013Enrolled211ConditionsLung DiseaseArmsPocket PATH (Personal Assistant for Tracking Health)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 7 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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  13. Patient Engagement and Medication Consistency with Adolescent Heart Transplant Recipients.Proceedings. IEEE International Conference on Healthcare Informatics · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emily M GeramitaDepartment of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA.
Annette J DeVito DabbsDepartment of Acute and Tertiary Care, University of Pittsburgh School of Nursing, Pittsburgh, PA.
Andrea F DiMartiniDepartments of Psychiatry and Surgery, University of Pittsburgh, Pittsburgh, PA.
Joseph M PilewskiDepartments of Medicine, Pediatrics, and Cell Biology, University of Pittsburgh, Pittsburgh, PA.
Galen E SwitzerDepartment of Medicine, University of Pittsburgh, and Center for Health Equity Research and Promotion, Veterans Administration Pittsburgh Healthcare System, Pittsburgh, PA.
Donna M PoslusznyDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA.
Larissa MyaskovskyDepartment of Internal Medicine, and Center for Healthcare Equity in Kidney Disease, University of New Mexico Health Sciences Center, Albuquerque, NM.
Mary Amanda DewDepartments of Psychiatry, Psychology, Epidemiology, Biostatistics, Nursing, and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

Phase III Trial of Pocket PATH: A Computerized Intervention to Promote Self-CareR01NR010711 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DE VITO DABBS, ANNETTE J · 2008 to 2012
$3.5M
University of Pittsburgh Clinical and Translational Science InstituteTL1TR000145 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$872k
NCATS NIH HHS TL1 TR000145NINR NIH HHS R01 NR010711
6 · The paper itself

Abstract

backgroundIn a randomized controlled trial, lung transplant recipients (LTRs) using a mobile health intervention, Pocket Personal Assistant for Tracking Health (Pocket PATH), showed better adherence to the medical regimen than LTRs receiving usual care during the first year posttransplant. We examined whether these effects were maintained beyond the end of the trial and evaluated other potential risk factors for long-term nonadherence.

methodsAdherence in 8 areas was evaluated at follow-up in separate LTR and family caregiver (collateral) assessments. Pocket PATH and usual care groups' nonadherence rates were compared; multivariable regression analyses then examined and controlled for other patient characteristics' associations with nonadherence.

resultsOne hundred five LTRs (75% of survivors) were assessed (M = 3.9 years posttransplant, SD = 0.8). Nonadherence rates in the past month were 23%-81% for self-care and lifestyle requirements (diet, exercise, blood pressure monitoring, spirometry), 13%-23% for immunosuppressants and other medications, and 4% for tobacco use, with 31% clinic appointment nonadherence in the past year. In multivariable analysis, the Pocket PATH group showed lower risk of nonadherence to lifestyle requirements (diet/exercise) than the usual care group (P < 0.05). Younger age and factors during the first year posttransplant (acute graft rejection, chronically elevated anxiety, less time rehospitalized, nonadherence at the final randomized controlled trial assessment) were each associated with nonadherence in at least 1 area at follow-up (P < 0.05).

conclusionsPocket PATH did not have sustained impact on most areas of the regimen, although we identified other risk factors for long-term nonadherence. Future work should explore strategies to facilitate sustained effects of mobile health interventions.

Indexed as

Drug MonitoringMobile ApplicationsAdultAgedAge FactorsFemaleFollow-Up StudiesGraft RejectionHumansImmunosuppressive AgentsLung TransplantationMaleMiddle AgedReminder SystemsSmartphoneTelemedicineImmunosuppressive Agents

Identifiers

PMID31335759
PMCPMC7170004
OpenAlexW2964048422

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.