Evidence map›Paper›PMID 31337704›Full record

ArticleThe Journal of biological chemistry2019

Magnesium transporter 1 (MAGT1) deficiency causes selective defects in

Mami Matsuda-Lennikov, Matthew Biancalana, Juan Zou, Juan C Ravell, Lixin Zheng, Chrysi Kanellopoulou, Ping Jiang, Giulia Notarangelo, Huie Jing, Evan Masutani and 4 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Metal Ions Within the Neuro-Immune-Tumor Axis.Journal of immunology research · 2026
    Review
  10. Article
  11. Case Report: NovelFrontiers in immunology · 2026
    Article
  12. Article
  13. Article
  14. TUSC3 regulates ERMA-mediated MgNature communications · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. XMEN Disease Associated with Recurrent Autoimmune Cytopenia and EBV-Positive Hodgkin Lymphoma: A Case ReportTurkish journal of haematology : official journal of Turkish Society of Haematology · 2025
    Article
  19. Article
  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Mami Matsuda-LennikovMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Matthew BiancalanaMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Juan ZouMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Juan C RavellMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0001-6687-2555
Lixin ZhengMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Chrysi KanellopoulouMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Ping JiangMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Giulia NotarangeloMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0003-3805-1834
Huie JingClinical Genomics Program, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Evan MasutaniMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.
Andrew J OlerBioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0002-6310-0434
Lisa Renee OlanoLaboratory of Neurotoxicology, National Institute of Mental Health, Bethesda, Maryland 20892.
Benjamin L SchulzUniversity of Queensland, School of Chemistry and Molecular Biology, Brisbane, St. Lucia, Queensland 4072, Australia.
Michael J LenardoMolecular Development of the Immune System Section, Laboratory of Immune System Biology, NIAID, National Institutes of Health, Bethesda, Maryland 20892 mlenardo@niaid.nih.gov.
National Institutes of Health · USNational Institute of Mental Health · USThe University of Queensland · AU

Funding

Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1M
New Roles of Magnesium as a Regulatory Ion in Immune Responses and Cell Behavior ZIAAI001187 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SU, HELEN · 2013 to 2024
$5.8M
6 · The paper itself

Abstract

Magnesium transporter 1 (MAGT1) critically mediates magnesium homeostasis in eukaryotes and is highly-conserved across different evolutionary branches. In humans, loss-of-function mutations in the

Indexed as

Cation Transport ProteinsEpstein-Barr Virus InfectionsGlycoproteinsGlycosylationHEK293 CellsHomeostasisHumansKiller Cells, NaturalMagnesiumMagnesium DeficiencyMembrane ProteinsMutationNeoplasmsTumor Suppressor ProteinsCation Transport ProteinsGlycoproteinsMagnesiumMagT1 protein, humanMembrane ProteinsTumor Suppressor ProteinsTUSC3 protein, humanEpstein-Barr virus (EBV) infectionglycoproteinglycosylationimmunodeficiencyimmunologyinfectionmagnesiummagnesium transporter 1 (MAGT1)N-linked glycosylation (NLG) complexoligosaccharyltransferase (OST)transporterX-linked magnesium deficiency with Epstein–Barr virus infection and neoplasia (XMEN)

Identifiers

PMID31337704
PMCPMC6746436
OpenAlexW2962830754

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.