ArticleFrontiers in public health2019
A Biopsychosocial Overview of the Opioid Crisis: Considering Nutrition and Gastrointestinal Health.
Article in Frontiers in public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Examination of the nutritional intake of patients undergoing opioid replacement therapy: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2023Pooled it
- The Test Based on Meta-Analysis on "Does Workaholism Prefer Task Performance or Contextual Performance?"Frontiers in psychology · 2022Pooled it
- Trial
- Medical Toxicology is the Overdose Specialty: Implications for the Dimensions and Continuum of Overdose Care.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026Article
- Effects of biopsychosocial complexity and pain-related factors on opioid prescription in patients with chronic musculoskeletal pain.Pain reports · 2025Article
- To smoothie or not to smoothie? A mixed-method approach of nutrition pilot intervention among individuals in opioid agonist treatment.BMC nutrition · 2025Article
- Experiences with healthy eating among individuals with opioid dependence: insights from a dietary assessment.BMC nutrition · 2025Article
- Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment.Clinics and practice · 2024Article
- Understanding the impact of the gut microbiome on opioid use disorder: Pathways, mechanisms, and treatment insights.Microbial biotechnology · 2024Review
- A Diagram of the Social-Ecological Conditions of Opioid Misuse and Overdose.International journal of environmental research and public health · 2023Review
- Cultivating Agents of Change in Medical Students: Addressing the Overdose Epidemic in the United States Through Enhancing Knowledge of Multimodal Pain Medicine and Increasing Accessibility via Open-Access, Web-Based Medical Education and Technology.JMIR medical education · 2023Article
- Patterns and Determinants of Weight Gain among People Who Use Drugs Undergoing Treatment for Recovery in Lebanon.Nutrients · 2023Article
- US medical school curriculum on opioid use disorder-a topic review of current curricular research and evaluation of winning student-designed opioid curricula for the 2021 Coalition on Physician Education in Substance Use Disorders curricular competition.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- Interventions to Reduce Opioid Use in Youth At-Risk and in Treatment for Substance Use Disorders: A Scoping Review.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2022Article
- The intergenerational persistence of opioid dependence: Evidence from administrative data.Health economics · 2022Article
- The Association of Opioid Use Disorder and COVID-19, a Longitudinal Study.International journal of preventive medicine · 2022Article
- Diet and Chronic Non-Cancer Pain: The State of the Art and Future Directions.Journal of clinical medicine · 2021Review
- Food insecurity partially mediates the association between drug use and depressive symptoms among men who have sex with men in Los Angeles, California.Public health nutrition · 2021Article
- Epigenetic Alterations in Prescription Opioid Misuse: New Strategies for Precision Pain Management.Genes · 2021Review
- Nutritional status and eating habits of people who use drugs and/or are undergoing treatment for recovery: a narrative review.Nutrition reviews · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The opioid crisis has reached epidemic proportions in the United States with rising overdose death rates. Identifying the underlying factors that contribute to addiction vulnerability may lead to more effective prevention strategies. Supply side environmental factors are a major contributing component. Psychosocial factors such as stress, trauma, and adverse childhood experiences have been linked to emotional pain leading to self-medication. Genetic and epigenetic factors associated with brain reward pathways and impulsivity are known predictors of addiction vulnerability. This review attempts to present a biopsychosocial approach that connects various social and biological theories related to the addiction crisis. The emerging role of nutrition therapy with an emphasis on gastrointestinal health in the treatment of opioid use disorder is presented. The biopsychosocial model integrates concepts from several disciplines, emphasizing multicausality rather than a reductionist approach. Potential solutions at multiple levels are presented, considering individual as well as population health. This single cohesive framework is based on the interdependency of the entire system, identifying risk and protective factors that may influence substance-seeking behavior. Nutrition should be included as one facet of a multidisciplinary approach toward improved recovery outcomes. Cross-disciplinary collaborative efforts, new ideas, and fiscal resources will be critical to address the epidemic.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.