Evidence map›Paper›PMID 31343254›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2019

Mesenchymal stem cells promote mesenteric vasodilation through hydrogen sulfide and endothelial nitric oxide.

Jan Te Winkel, Quincy E John, Brian D Hosfield, Natalie A Drucker, Amitava Das, Ken R Olson, Troy A Markel

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. CBS-HJournal of advanced research · 2023
    Article
  9. Article
  10. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration.American journal of physiology. Heart and circulatory physiology · 2022
    Review
  11. Review
  12. Article
  13. American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jan Te WinkelDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Quincy E JohnDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Brian D HosfieldDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Natalie A DruckerDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Amitava DasDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Ken R OlsonIndiana University School of Medicine, South Bend, Indiana.
Troy A MarkelDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Indiana University School of MedicineIndiana University Health · USIndiana University – Purdue University Indianapolis · US

Funding

Mesenchymal Stromal Cells Modulate Intestinal Mesenteric Endothelium Via Hydrogen SulfideK08DK113226 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MARKEL, TROY A · 2018 to 2021
$603k
NIDDK NIH HHS K08 DK113226
6 · The paper itself

Abstract

Mesenteric ischemia is a devastating process that can result in intestinal necrosis. Mesenchymal stem cells (MSCs) are becoming a promising treatment modality. We hypothesized that

Indexed as

AdiponectinAnimalsArteriolesCystathionine beta-SynthaseGene Knockdown TechniquesHumansHydrogen SulfideIn Vitro TechniquesMaleMesenchymal Stem CellsMesenteric IschemiaMiceMice, Inbred C57BLNitric Oxide Synthase Type IIIResistinSplanchnic CirculationAdiponectinAdipoq protein, mouseCystathionine beta-SynthaseHydrogen SulfideNitric Oxide Synthase Type IIINos3 protein, mouseResistinRetn protein, mouseeNOShydrogen sulfidemesenchymal stromal cellsmesenteric vesselspressure myography

Identifiers

PMID31343254
PMCPMC6842994
OpenAlexW2963377866

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.