Evidence map›Paper›PMID 31348974›Full record

ReviewBiochimica et biophysica acta. Reviews on cancer2019

Sodium homeostasis in the tumour microenvironment.

Theresa K Leslie, Andrew D James, Fulvio Zaccagna, James T Grist, Surrin Deen, Aneurin Kennerley, Frank Riemer, Joshua D Kaggie, Ferdia A Gallagher, Fiona J Gilbert and 1 more

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biochimica et biophysica acta. Reviews on cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Cancer: A bioelectric disease?Clinical and translational medicine · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. NaFrontiers in chemistry · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Theresa K LeslieDepartment of Biology, University of York, Heslington, York YO10 5DD, UK; York Biomedical Research Institute, University of York, Heslington, York YO10 5DD, UK.
Andrew D JamesDepartment of Biology, University of York, Heslington, York YO10 5DD, UK; York Biomedical Research Institute, University of York, Heslington, York YO10 5DD, UK.
Fulvio ZaccagnaDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
James T GristDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Surrin DeenDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Aneurin KennerleyYork Biomedical Research Institute, University of York, Heslington, York YO10 5DD, UK; Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
Frank RiemerDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Joshua D KaggieDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Ferdia A GallagherDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
Fiona J GilbertDepartment of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
William J BrackenburyDepartment of Biology, University of York, Heslington, York YO10 5DD, UK; York Biomedical Research Institute, University of York, Heslington, York YO10 5DD, UK. Electronic address: william.brackenbury@york.ac.uk.
University of Cambridge · GBUniversity of York · GB

Funding

Breast Cancer Now 2015NOVPHD572Cancer Research UK 16465Cancer Research UK 16628Cancer Research UK 25922Cancer Research UK 27150Cancer Research UK 30380Cancer Research UK A25922
6 · The paper itself

Abstract

The concentration of sodium ions (Na

Indexed as

Adenosine TriphosphateCell SizeHomeostasisHumansNeoplasmsSodiumTumor MicroenvironmentAdenosine TriphosphateSodiumChannelsMicroenvironmentMRISodiumTransportersTumours

Identifiers

PMID31348974
PMCPMC7115894
OpenAlexW2964049994

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.