Evidence map›Paper›PMID 31357671›Full record

ArticleToxins2019

Label-Free Fluorescent Aptasensor for Ochratoxin-A Detection Based on CdTe Quantum Dots and (

Li Liu, Zafar Iqbal Tanveer, Keqiu Jiang, Qingwen Huang, Jinghui Zhang, Yongjiang Wu, Zheng Han

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Li LiuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Zafar Iqbal TanveerCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Keqiu JiangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Qingwen HuangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Jinghui ZhangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Yongjiang WuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. yjwu@zju.edu.cn.ORCID 0000-0003-0246-9067
Zheng HanInstitute for Agro-food Standards and Testing Technology, Shanghai Key Laboratory of Protected Horticultural Technology, Laboratory of Quality and Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China. hanzheng@saas.sh.cn.
Zhejiang University · CNShanghai Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the widespread contamination of ochratoxin A (OTA), it is of significant importance for detecting OTA in foods and traditional Chinese medicine (TCM). In this study, a novel label-free fluorescent aptasensor utilizing the interaction between OTA-triggered antiparallel G-quadruplex and (N-methyl-4-pyridy) porphyrin (TMPyP) for the rapid and sensitive determination of OTA was established. The fluorescence of CdTe quantum dots (QDs) could be quenched by TMPyP. In the presence of analyte (OTA), the aptamer could recognize OTA and transform from a random coil to the antiparallel G-quadruplex. The interaction between G-quadruplex and TMPyP could release CdTe QDs from TMPyP, and thus recover the fluorescence of CdTe QDs. Under optimized conditions, the detection limit of the designed aptasensor was 0.16 ng mL

Indexed as

G-QuadruplexesAptamers, NucleotideAstragalus PlantCadmium CompoundsFluorescenceOchratoxinsPorphyrinsQuantum DotsTelluriumAptamers, NucleotideCadmium Compoundscadmium tellurideochratoxin AOchratoxinsPorphyrinsTelluriumtetra(4-N-methylpyridyl)porphineG-quadruplex aptamerochratoxin Aporphyrinquantum dots

Identifiers

PMID31357671
PMCPMC6724026
OpenAlexW2965466448

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.