Evidence map›Paper›PMID 31361295›Full record

ArticleCardiovascular journal of Africa

Effects of atorvastatin on time-dependent change of fast sodium current in simulated acute ischaemic ventricular myocytes.

Hongshi Li, Zheng Wan, Xiaolong Li, Tianming Teng, Xin Du, Jing Nie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hongshi LiDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070, PR China.
Zheng WanDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070, PR China . Email: wanzh_md@126.com.
Xiaolong LiDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070, PR China.
Tianming TengDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070, PR China.
Xin DuDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070, PR China.
Jing NieDepartment of Cardiology, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin 300070, PR China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOur previous experiments showed that the transient sodium current (I

methodsLeft ventricular myocytes were isolated from Wistar rats and randomly divided into two groups: a control group (normal to simulated ischaemia) and a statin group (normal to simulated ischaemia with 5 µmol/l atorvastatin). The I

resultsIn the control group, normalised I

conclusionOur results suggest that, in the early stages of ischaemia, changes in I

Indexed as

AnimalsAnti-Arrhythmia AgentsArrhythmias, CardiacAtorvastatinFemaleHeart RateHeart VentriclesIon Channel GatingKineticsMaleMembrane PotentialsMyocardial IschemiaMyocytes, CardiacRats, WistarSodiumSodium ChannelsAnti-Arrhythmia AgentsAtorvastatinSodiumSodium Channelsmembrane potentialsodiumstatinventricular arrhythmiaventricular myocytes

Identifiers

PMID31361295
PMCPMC8802376
OpenAlexW2985423485

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.