Evidence map›Paper›PMID 31361520›Full record

ArticleSLAS discovery : advancing life sciences R & D2020

A Cell-Based

Tara Walhart, Erin Isaacson-Wechsler, Kean-Hooi Ang, Michelle Arkin, Sharof Tugizov, Joel M Palefsky

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in SLAS discovery : advancing life sciences R & D, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Nanotechnological approaches for pentamidine delivery.Drug delivery and translational research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tara WalhartDepartment of Community Health Systems, School of Nursing, University of California, San Francisco, CA, USA.ORCID 0000-0002-1176-3973
Erin Isaacson-WechslerDepartment of Infectious Disease, Palefsky Laboratory, School of Medicine, University of California, San Francisco, CA, USA.
Kean-Hooi AngDepartment of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, CA, USA.
Michelle ArkinDepartment of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, CA, USA.
Sharof TugizovDepartment of Infectious Disease, Palefsky Laboratory, School of Medicine, University of California, San Francisco, CA, USA.
Joel M PalefskyDepartment of Infectious Disease, Palefsky Laboratory, School of Medicine, University of California, San Francisco, CA, USA.
University of California, San Francisco · US

Funding

INTERVENTIONS FOR PREVENTING &MANAGING CHRONIC ILLNESST32NR007091 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Cheryl L Giscombe, Cathi Barbra Propper · 1996 to 2026
$11.8M
HIV/AIDS NURSING CARE AND PREVENTIONT32NR007081 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAWSON-ROSE, CAROL, VLAHOV, DAVID · 1995 to 2016
$3.8M
Role of oral herpesvirus microbiota in pathogenesis of HIV mother to child transmissionR01DE028129 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TUGIZOV, SHAROF M · 2018 to 2022
$2.6M
Role of HIV in acceleration of HPV malignancyR01CA232887 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TUGIZOV, SHAROF M · 2019 to 2023
$1.8M
Identification of Novel Inhibitors of Human Papillomoavirus InfectionF31NR013863 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WALHART, TARA · 2012 to 2014
$106k
NCI NIH HHS R01 CA232887NIDCR NIH HHS R01 DE028129NINR NIH HHS F31 NR013863NINR NIH HHS T32 NR007081NINR NIH HHS T32 NR007091
6 · The paper itself

Abstract

Like cervical cancer, anal cancer is caused by human papillomavirus (HPV). HPV is the most common sexually transmitted agent and is found in the anal canal of almost all HIV-positive men who have sex with men (MSM). Rates of HPV anal cancer are disproportionately higher in this population. Although the nanovalent HPV vaccine is efficacious in protecting against oncogenic HPV types, a substantial proportion of MSM remains unvaccinated and anal HPV infection continues to be an important public health burden. Therefore, it is important to identify strategies to prevent HPV infection. We report on two promising and interlinked strategies: (1) the development of a cell-based

Indexed as

Drug Evaluation, PreclinicalGenes, ReporterAntiviral AgentsCell LineDrug ApprovalHigh-Throughput Screening AssaysHuman papillomavirus 16HumansLuminescent ProteinsPlasmidsReproducibility of ResultsUnited StatesUnited States Food and Drug AdministrationAntiviral AgentsLuminescent Proteinshigh-throughput screeningHPV-16papillomaviruspseudovirusrepurposed

Identifiers

PMID31361520
PMCPMC6925341
OpenAlexW2966108231

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.