Evidence map›Paper›PMID 31368617›Full record

ArticleTraffic (Copenhagen, Denmark)2019

Copper blocks V-ATPase activity and SNARE complex formation to inhibit yeast vacuole fusion.

Gregory E Miner, Katherine D Sullivan, Chi Zhang, Logan R Hurst, Matthew L Starr, David A Rivera-Kohr, Brandon C Jones, Annie Guo, Rutilio A Fratti

Open access · greenAbstract read
In one paragraph

Article in Traffic (Copenhagen, Denmark), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Reversible binding of divalent cations toFrontiers in molecular biosciences · 2023
    Review
  7. Article
  8. The Plant V-ATPase.Frontiers in plant science · 2022
    Review
  9. Copper metabolism in Saccharomyces cerevisiae: an update.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Gregory E MinerDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Katherine D SullivanDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Chi ZhangDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Logan R HurstDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Matthew L StarrDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
David A Rivera-KohrDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Brandon C JonesDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Annie GuoDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Rutilio A FrattiDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois.ORCID 0000-0001-9109-6666
University of Illinois Urbana-Champaign · US

Funding

Allosteric Regulation of SNAREs and the Rab GEF Mon1 by PhosphoinositidesR01GM101132 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI FRATTI, RUTILIO A · 2012 to 2016
$1.4M
NIGMS NIH HHS R01 GM101132
6 · The paper itself

Abstract

The accumulation of copper in organisms can lead to altered functions of various pathways and become cytotoxic through the generation of reactive oxygen species. In yeast, cytotoxic metals such as Hg

Indexed as

Adenosine TriphosphatasesCarrier ProteinsCell MembraneCopperCytoplasmMembrane FusionMolecular ChaperonesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSNARE ProteinsVacuolesVesicular Transport ProteinsAdenosine TriphosphatasesCarrier ProteinsCopperMolecular ChaperonesSaccharomyces cerevisiae ProteinsSNARE ProteinsVesicular Transport ProteinsFre6membrane fusionNyv1Sec17SNAREVam3Vam7V-ATPase

Identifiers

PMID31368617
PMCPMC6800785
OpenAlexW2965944782

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.