ReviewMicromachines2019
Optical Tweezers: Phototoxicity and Thermal Stress in Cells and Biomolecules.
Review in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Lab-in-a-Droplet: Utilizing Acoustic Levitation for Miniaturized Sample Preparation and LC-MS/MS, Exemplified by Measurement of Vitamin D in Serum.Analytical chemistry · 2026Article
- High-efficiency generation of stably transduced monoclonal cell lines via a laser-induced jetting microfluidic platform.Analytical and bioanalytical chemistry · 2026Article
- Controlling the sign of optical forces using metaoptics.Nature communications · 2026Article
- Development of electromagnetic tweezers for single-molecule energetics of kinesin.Biophysics and physicobiology · 2026Article
- Microhand Platform Equipped with Plate-Shaped End-Effectors Enables Precise Probing of Intracellular Structure Contribution to Whole-Cell Mechanical Properties.Micromachines · 2025Article
- Unveiling Exciton-Plasmon Polariton Coupling Regions via Polarization-Enhanced Optical Nanoscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Trigger factor accelerates nascent chain compaction and folding.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Streaming-based Tweezers for Routing, Engineering, and Manipulation of multiparticles: STREAM.Microsystems & nanoengineering · 2025Article
- Editorial on Optical Tweezers for the 15th Anniversary of Micromachines.Micromachines · 2024Article
- Acoustography by Beam Engineering and Acoustic Control Node: BEACON.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Optical tweezers in biomedical research - progress and techniques.Journal of medicine and life · 2024Review
- Thermo-optical tweezers based on photothermal waveguides.Microsystems & nanoengineering · 2024Article
- Recent Advances in Research from Nanoparticle to Nano-Assembly: A Review.Nanomaterials (Basel, Switzerland) · 2024Review
- Photon-efficient optical tweezers via wavefront shaping.Science advances · 2024Article
- Red blood cell flickering activity locally controlled by holographic optical tweezers.iScience · 2024Article
- Plasmonic dielectric antennas for hybrid optical nanotweezing and optothermoelectric manipulation of single nanosized extracellular vesicles.Advanced optical materials · 2024Article
- Integrated Microfluidics for Single-Cell Separation and On-Chip Analysis: Novel Applications and Recent Advances.Small science · 2024Article
- Continuous Perfusion Experiments on 3D Cell Proliferation in Acoustic Levitation.Micromachines · 2024Article
- On-Axis Optical Trapping with Vortex Beams: The Role of the Multipolar Decomposition.ACS photonics · 2024Article
- Raman cell sorting for single-cell research.Frontiers in bioengineering and biotechnology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
For several decades optical tweezers have proven to be an invaluable tool in the study and analysis of myriad biological responses and applications. However, as with every tool, they can have undesirable or damaging effects upon the very sample they are helping to study. In this review the main negative effects of optical tweezers upon biostructures and living systems will be presented. There are three main areas on which the review will focus: linear optical excitation within the tweezers, non-linear photonic effects, and thermal load upon the sampled volume. Additional information is provided on negative mechanical effects of optical traps on biological structures. Strategies to avoid or, at least, minimize these negative effects will be introduced. Finally, all these effects, undesirable for the most, can have positive applications under the right conditions. Some hints in this direction will also be discussed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.