Evidence map›Paper›PMID 31385262›Full record

SynthesisJournal of racial and ethnic health disparities2019

Systematic Review of Chronic Discrimination and Changes in Biology During Pregnancy Among African American Women.

Carlye Chaney, Marcela Lopez, Kyle S Wiley, Caitlin Meyer, Claudia Valeggia

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of racial and ethnic health disparities, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Experiences of Discrimination and DNA Methylation Among Black Nulliparous Women.Journal of racial and ethnic health disparities · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Prenatal Stress and Maternal Role in Neurodevelopment.Annual review of developmental psychology · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlye ChaneyDepartment of Anthropology, Yale University, 10 Sachem St, New Haven, CT, 06511, USA. Carlye.Chaney@yale.edu.ORCID 0000-0003-0733-6079
Marcela LopezDepartment of Anthropology, Yale University, 10 Sachem St, New Haven, CT, 06511, USA.
Kyle S WileyDepartment of Anthropology, Yale University, 10 Sachem St, New Haven, CT, 06511, USA.
Caitlin MeyerHarvey Cushing/John Hay Whitney Medical Library, Yale University, New Haven, CT, USA.
Claudia ValeggiaDepartment of Anthropology, Yale University, 10 Sachem St, New Haven, CT, 06511, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Profound racial health disparities in maternal and infant health exist in the USA. Discrimination based on race may contribute to these disparities, but the biological pathways through which racial discrimination acts on health are not fully known. Even less is known about these pathways during development. Examining how racial discrimination becomes biology is paramount because it may shed light on how and when such social forces result in lasting biological consequences for health and wellbeing. To begin exploring this issue, we performed a systematic review of the relationships between experiences of chronic racial discrimination and relevant biomarkers measured during pregnancy among African American women. The literature search included studies published prior to August 2018 in the MEDLINE, Embase, and PsycINFO databases, and 11 studies met our inclusion criteria. We evaluated the articles based on the biological system that the authors investigated, which included the immune, neuroendocrine, and cardiovascular systems. We found that the current literature provides preliminary evidence that experiences of chronic racial discrimination are associated with changes in maternal biology during pregnancy. However, the literature was limited in both quantity and quality. We found only 11 studies that addressed this subject, four of which only provided indirect evidence, and many studies had small sample sizes. Future work in this area should develop more informative methods that consider the interaction between interpersonal and structural racial discrimination, individual variation, and sociocultural factors. We conclude researchers should continue to work in this area and focus on developing more effective study designs and larger sample sizes.

Indexed as

Black or African AmericanRacismAntibodies, ViralBiomarkersBirth WeightBlood PressureCytokinesFemaleHumansHypothalamo-Hypophyseal SystemImmunocompetenceInfant, NewbornInflammationPituitary-Adrenal SystemPregnancyPregnant PeopleAntibodies, ViralBiomarkersCytokinesMaternal healthPregnancy outcomesRacial discrimination

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.