Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Distinct Roles of Dopamine and Noradrenaline in Incidental Memory.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Disentangling the roles of dopamine and noradrenaline in the exploration-exploitation tradeoff during human decision-making.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- L-DOPA administration shifts the stability-flexibility balance towards attentional capture by distractors during a visual search task.Psychopharmacology · 2022Trial
- Attention-enhancing effects of propranolol and synergistic effects with nicotine.Cognitive, affective & behavioral neuroscience · 2020Trial
- Non-invasive transcutaneous vagus nerve stimulation during memory retrieval enhances recollection of emotionally salient memories.Scientific reports · 2026Article
- Modification of Neural Circuit Functions by Microglial P2Y6 Receptors in Health and Neurodegeneration.Molecular neurobiology · 2025Review
- Neurotransmitters' white matter mapping unveils the neurochemical fingerprints of stroke.Nature communications · 2025Article
- A narrative on the neurobiological roots of attachment-system functioning.Communications psychology · 2024Review
- Consistency within change: Evaluating the psychometric properties of a widely used predictive-inference task.Behavior research methods · 2024Article
- Iron administered in the neonatal period changed memory, brain monoamine levels, and BDNF mRNA expression in adult Sprague-Dawley rats.Pharmacological reports : PR · 2024Article
- Post-exposure self-recovery reverses oxidative stress, ameliorates pathology and neurotransmitters imbalance and rescues spatial memory after time-dependent aluminum exposure in rat brain.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- Changes in pupil size track self-control failure.Experimental brain research · 2024Article
- The effect of reward-induced arousal on the success and precision of episodic memory retrieval.Scientific reports · 2024Article
- Let's Shape Learning Into Lasting Memories.Neuroscience insights · 2024Article
- Declining locus coeruleus-dopaminergic and noradrenergic modulation of long-term memory in aging and Alzheimer's disease.Neuroscience and biobehavioral reviews · 2023Review
- Cerebrospinal fluid and positron-emission tomography biomarkers for noradrenergic dysfunction in neurodegenerative diseases: a systematic review and meta-analysis.Brain communications · 2023Review
- Article
- The regulatory role of AP-2β in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential.Cell & bioscience · 2022Review
- Induced negative arousal modulates the speed of visual working memory consolidation.Emotion (Washington, D.C.) · 2022Article
- Regulation of cocaine seeking behavior by locus coeruleus noradrenergic activity in the ventral tegmental area is time- and contingency-dependent.Frontiers in neuroscience · 2022Article
- Phasic pupillary responses modulate object-based attentional prioritization.Attention, perception & psychophysics · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
Episodic memory is sensitive to the influence of neuromodulators, such as dopamine and noradrenaline. These influences are considered important in the expression of several known memory biases, though their specific role in memory remains unclear. Using pharmacological agents with relatively high selectivity for either dopamine (400 mg amisulpride) or noradrenaline (40 mg propranolol) we examined their specific contribution to incidental memory. In a double-blind placebo-controlled human study (30 females, 30 males in total), we show that a memory selectivity bias was insensitive to propranolol but sensitive to amisulpride, consistent with a dominant influence from dopamine. By contrast, a putative arousal-induced memory boosting effect was insensitive to amisulpride but was sensitive to propranolol, consistent with a dominant noradrenaline effect. Thus, our findings highlight specific functional roles for dopamine and noradrenaline neurotransmission in the expression of incidental memory.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.