Evidence map›Paper›PMID 31409051›Full record

ArticleInternational journal of molecular sciences2019

A Long Polymorphic GT Microsatellite within a Gene Promoter Mediates Non-Imprinted Allele-Specific DNA Methylation of a CpG Island in a Goldfish Inter-Strain Hybrid.

Jianbo Zheng, Haomang Xu, Huiwen Cao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jianbo ZhengZhejiang Institute of Freshwater Fisheries, Huzhou 313001, China. 21207054@zju.edu.cn.
Haomang XuCollege of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Huiwen CaoCollege of Life Sciences, Zhejiang University, Hangzhou 310058, China.
Zhejiang University · CNZhejiang Institute of Freshwater Fisheries · CN

Funding

Chen Luo 2016C02055-1
6 · The paper itself

Abstract

It is now widely accepted that allele-specific DNA methylation (ASM) commonly occurs at non-imprinted loci. Most of the non-imprinted ASM regions observed both within and outside of the CpG island show a strong correlation with DNA polymorphisms. However, what polymorphic cis-acting elements mediate non-imprinted ASM of the CpG island remains unclear. In this study, we investigated the impact of polymorphic GT microsatellites within the gene promoter on non-imprinted ASM of the local CpG island in goldfish. We generated various goldfish heterozygotes, in which the length of GT microsatellites or some non-repetitive sequences in the promoter of

Indexed as

DNA MethylationMicrosatellite RepeatsAllelesAnimalsChimeraCpG IslandsCrosses, GeneticFemaleGenomic ImprintingGoldfishMalePolymorphism, GeneticPromoter Regions, Geneticallele-specific DNA methylationcis-acting regulatory polymorphismsCpG islandGT microsatellitesnon-imprinted gene

Identifiers

PMID31409051
PMCPMC6721770
OpenAlexW2967766061

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.