Evidence map›Paper›PMID 31412657›Full record

SynthesisGenes2019

Meta-Analysis of Cancer Triploidy: Rearrangements of Genome Complements in Male Human Tumors Are Characterized by XXY Karyotypes.

Ninel M Vainshelbaum, Pawel Zayakin, Regina Kleina, Alessandro Giuliani, Jekaterina Erenpreisa

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Ploidy status analysis in small cell lung cancer cells and its use in cytopathological diagnosis.International journal of clinical and experimental pathology · 2025
    Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ninel M VainshelbaumCancer Research Division, Latvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia.
Pawel ZayakinCancer Research Division, Latvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia.ORCID 0000-0002-5336-3484
Regina KleinaDepartment of Pathology, Riga Stradins University, LV-1007 Riga, Latvia.
Alessandro GiulianiEnvironment and Health Department, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-4640-804X
Jekaterina ErenpreisaCancer Research Division, Latvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia. katrina@biomed.lu.lv.ORCID 0000-0002-2870-7775
Latvian Biomedical Research and Study Centre · LVIstituto Superiore di Sanità · ITRiga Stradiņš University · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triploidy in cancer is associated with poor prognosis, but its origins remain unclear. Here, we attempted to differentiate between random chromosomal and whole-genome origins of cancer triploidy.

Indexed as

Abnormal KaryotypeGenomic InstabilityTriploidyChromosomes, Human, XChromosomes, Human, YDNA, NeoplasmHumansMaleNeoplasmsDNA, Neoplasmcancer near-triploidydigynykaryotype meta-analysismale tumorswhole-genome rearrangementsXXY

Identifiers

PMID31412657
PMCPMC6723511
OpenAlexW2969009267

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.