Evidence map›Paper›PMID 31412898›Full record

ArticleBMC biology2019

Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium.

Julia K Johansson, Viivi I Karema-Jokinen, Satu Hakanen, Antti Jylhä, Hannu Uusitalo, Maija Vihinen-Ranta, Heli Skottman, Teemu O Ihalainen, Soile Nymark

Open access · goldAbstract read
In one paragraph

Article in BMC biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Cell-cell interaction in the pathogenesis of inherited retinal diseases.Frontiers in cell and developmental biology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Julia K JohanssonBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Viivi I Karema-JokinenBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Satu HakanenDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland.
Antti JylhäBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Hannu UusitaloBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Maija Vihinen-RantaDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland.
Heli SkottmanBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Teemu O IhalainenBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Soile NymarkBioMediTech, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. soile.nymark@tuni.fi.ORCID 0000-0002-9274-0123
Tampere University · FIUniversity of Jyväskylä · FITampere University of Applied Sciences · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVoltage-gated sodium (Na

resultsOur work demonstrates that several subtypes of Na

conclusionsTaken together, our study shows that Na

Indexed as

AnimalsHuman Embryonic Stem CellsHumansMiceMice, Inbred C57BLPatch-Clamp TechniquesPhagocytosisRetinal Pigment EpitheliumSignal TransductionSodium ChannelsSodium ChannelsIon channelsNavPatch clampPhagocytosisPhotoreceptorsRetinaRPE

Identifiers

PMID31412898
PMCPMC6694495
OpenAlexW2969190851

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.