ArticleScientific reports2019
Linking type 2 diabetes mellitus, cardiac hypertrophy and depression in a diurnal animal model.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Exercise Reduces Glucose Intolerance, Cardiac Inflammation and Adipose Tissue Dysfunction inInternational journal of molecular sciences · 2024Article
- Effects of photoperiod and food on glucose intolerance and subsequent ocular pathology in the fat sand rat.Scientific reports · 2024Article
- The relationship between oxidative balance score and circadian syndrome: evidence from the NHANES 2005-2018.Frontiers in endocrinology · 2024Article
- Dietary Carbohydrate as Glycemic Load, Not Fat, Coupled withNutrients · 2022Article
- Minocycline as heart conditioning agent in experimental type 2 diabetes mellitus - an antibacterial drug in heart protection.Naunyn-Schmiedeberg's archives of pharmacology · 2022Article
- Beneficial effects of voluntary wheel running on activity rhythms, metabolic state, and affect in a diurnal model of circadian disruption.Scientific reports · 2022Article
- Protective Roles of Apigenin Against Cardiometabolic Diseases: A Systematic Review.Frontiers in nutrition · 2022Review
- Circadian rhythms-related disorders in diurnal fat sand rats under modern lifestyle conditions: A review.Frontiers in physiology · 2022Review
- Circadian disruption by short light exposure and a high energy diet impairs glucose tolerance and increases cardiac fibrosis in Psammomys obesus.Scientific reports · 2021Article
- The darkness and the light: diurnal rodent models for seasonal affective disorder.Disease models & mechanisms · 2021Review
- Beneficial effects of daytime high-intensity light exposure on daily rhythms, metabolic state and affect.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It was recently suggested that the Metabolic Syndrome should be renamed to "Circadian Syndrome". In this context, we explored the effects of living under standard laboratory conditions, where light is the only cycling variable (relevant to human modern life), in a diurnal mammal, on the relationships between affective-like pathology, type 2 diabetes mellitus (T2DM), and cardiac hypertrophy. After 20 weeks, some of the animals spontaneously developed T2DM, depressive and anxiety-like behavior and cardiac hypertrophy. There were significant correlations between levels of anxiety-like behavior and glucose tolerance, and between heart/total body weight ratio and glucose tolerance. Our data suggest a relationship between the development of T2DM, emotional and cardiac pathology as seen in diurnal humans. Furthermore, our data show a possible relationship between reduced daily cycling cues in the laboratory and what has been regularly termed "Metabolic Syndrome" and recently proposed by us to be renamed to "Circadian Syndrome".
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.