Evidence mapPaperPMID 31415212Full record

ArticleAnnals of the American Thoracic Society2019

Association of Metformin Initiation and Risk of Asthma Exacerbation. A Claims-based Cohort Study.

Tianshi David Wu, Corinne A Keet, Ashraf Fawzy, Jodi B Segal, Emily P Brigham, Meredith C McCormack

Open access · greenAbstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Gestational diabetes and childhood lung function at age 8 to 9 years in a diverse US cohort.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  5. Article
  6. Metformin for asthma exacerbations.The Cochrane database of systematic reviews · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Non-T2 asthma.Current opinion in pulmonary medicine · 2025
    Review
  11. Article
  12. The role of type 2 diabetes in the severity of adult asthma.Current opinion in allergy and clinical immunology · 2025
    Review
  13. Diabetes-inducing effects of bronchial asthma.World journal of diabetes · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Impact of metabolic and weight components on incident asthma using a real-world cohort.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tianshi David WuDivision of Pulmonary and Critical Care Medicine.
Corinne A KeetDivision of Pediatric Allergy and Immunology, and.
Ashraf FawzyDivision of Pulmonary and Critical Care Medicine.
Jodi B SegalDivision of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Emily P BrighamDivision of Pulmonary and Critical Care Medicine.
Meredith C McCormackDivision of Pulmonary and Critical Care Medicine.
Pulmonary and Critical Care Associates · USJohns Hopkins University · US

Funding

The effect of a housing mobility program on environmental exposures and asthma morbidityR01ES026170 · JOHNS HOPKINS UNIVERSITY · 2025 to 2025
$598k
NIAID NIH HHS K24 AI114769NIAID NIH HHS U01 AI125290NIEHS NIH HHS F32 ES028576NIEHS NIH HHS F32 ES028578NIEHS NIH HHS K23 ES029105NIEHS NIH HHS P50 ES018176NIEHS NIH HHS R01 ES023447NIEHS NIH HHS R01 ES026170
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAsthmaDatabases, FactualDiabetes MellitusDisease ProgressionEmergency Service, HospitalFemaleHospitalizationHumansMaleMetforminMiddle AgedPropensity ScoreProportional Hazards ModelsRetrospective StudiesTreatment OutcomeMetforminadministrative datametabolic dysfunctionmetforminpharmacoepidemiology

Identifiers

PMID31415212
PMCPMC6956833
OpenAlexW2968841761

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.