ArticleMolecules (Basel, Switzerland)2019
A Brønsted Acid-Catalyzed Multicomponent Reaction for the Synthesis of Highly Functionalized γ-Lactam Derivatives.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Exploring the Synthetic Potential of γ-Lactam Derivatives Obtained from a Multicomponent Reaction-Applications as Antiproliferative Agents.Molecules (Basel, Switzerland) · 2022Article
- Multicomponent Synthesis of Unsaturated γ-Lactam Derivatives. Applications as Antiproliferative Agents through the Bioisosterism Approach: Carbonyl vs. Phosphoryl Group.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Experimental and theoretical studies on the synthesis of 1,4,5-trisubstituted pyrrolidine-2,3-diones.Beilstein journal of organic chemistry · 2022Article
- Article
- A Multicomponent Protocol for the Synthesis of Highly Functionalized γ-Lactam Derivatives and Their Applications as Antiproliferative Agents.Pharmaceuticals (Basel, Switzerland) · 2021Article
- One-pot multi-component synthesis of new bis-pyridopyrimidine and bis-pyrimidoquinolone derivatives.Heliyon · 2020Article
- Modern Strategies for Heterocycle Synthesis.Molecules (Basel, Switzerland) · 2020Article
- Rapid and catalyst free synthesis of new bis(benzo[RSC advances · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Brønsted acids catalyze a multicomponent reaction of benzaldehyde with amines and diethyl acetylenedicarboxylate to afford highly functionalized γ-lactam derivatives. The reaction consists of a Mannich reaction of an enamine to an imine, both generated
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.