Evidence map›Paper›PMID 31423489›Full record

ArticleJournal of clinical nutrition and food science2019

Vitamin D Levels in Patients with Colorectal Cancer and Matched Household Members.

Marissa B Savoie, Alan Paciorek, Li Zhang, Nilli Sommovilla, Alan P Venook, Erin L Van Blarigan, Katherine Van Loon

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of clinical nutrition and food science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marissa B SavoieHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, USA.
Alan PaciorekHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, USA.
Li ZhangHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, USA.
Nilli SommovillaDepartment of Medicine, Georgetown University, Washington, DC, USA.
Alan P VenookHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, USA.
Erin L Van BlariganHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, USA.
Katherine Van LoonHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, USA.
University of California, San Francisco · USUCSF Helen Diller Family Comprehensive Cancer Center · USGeorgetown University · US

Funding

Diet After Colorectal Cancer : Observational Studies to Behavioral InterventionsK07CA197077 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAN BLARIGAN, ERIN LYNN · 2016 to 2020
$885k
NCI NIH HHS K07 CA197077
6 · The paper itself

Abstract

backgroundVitamin D levels, as measured by 25-hydroxyvitamin-D [25(OH) D], are inversely related to the risk of developing colorectal cancer (CRC). Given shared demographic and lifestyle factors among members of the same household, we sought to examine vitamin D levels and associated lifestyle factors in household members of CRC patients.

methodsThirty patients with pathologically confirmed CRC were enrolled prior to oncologic therapy along with unrelated household members who were matched for age (+/- 5 years) and race. In addition to serum blood draws for 25(OH)D levels at baseline and six-month follow-up, questionnaires collected gender, vitamin use, body mass index, family history of CRC, race, dietary vitamin D, UV exposure, and exercise.

resultsMedian serum 25(OH) D levels were 26.8 ng/mL for CRC patients versus 27.3 for household members (P=0.89). Vitamin-D associated factors such as dietary vitamin D intake, UV exposure, gender, multivitamin use, vitamin D supplement use, and family history of CRC were not significantly different between CRC patients and paired household members (P>0.05). Household members were more likely than CRC patients to be overweight and to exercise more.

conclusionsVitamin D levels and many associated lifestyle factors were not significantly different between CRC patients and unrelated paired household members. Given comparable vitamin D levels, further investigation into whether age-matched household members of CRC patients may be at increased risk for CRC is warranted.

Indexed as

Colorectal cancerHousehold membersVitamin D

Identifiers

PMID31423489
PMCPMC6697376
OpenAlexW3000111706

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.