Evidence map›Paper›PMID 31428573›Full record

ArticleFrontiers in oncology2019

Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry?

Andrés Valdivia, Gabriel Mingo, Varina Aldana, Mauricio P Pinto, Marco Ramirez, Claudio Retamal, Alfonso Gonzalez, Francisco Nualart, Alejandro H Corvalan, Gareth I Owen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Article
  5. Review
  6. Article
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  20. An Overview of Angiogenesis in Bladder Cancer.Current oncology reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Andrés ValdiviaFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Gabriel MingoFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Varina AldanaFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Mauricio P PintoFaculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Marco RamirezFaculty of Medicine, Universidad de Chile, Santiago, Chile.
Claudio RetamalFaculty of Medicine and Science, Center of Cellular Biology and Biomedicine (CEBICEM), Universidad San Sebastian, Santiago, Chile.
Alfonso GonzalezFaculty of Medicine and Science, Center of Cellular Biology and Biomedicine (CEBICEM), Universidad San Sebastian, Santiago, Chile.
Francisco NualartFaculty of Biological Sciences, Universidad de Concepcion, Concepción, Chile.
Alejandro H CorvalanFaculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Gareth I OwenFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pontificia Universidad Católica de Chile · CLSan Sebastián University · CLMillennium Institute on Immunology and Immunotherapy · CLUniversity of Chile · CLUniversity of Concepción · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term vasculogenic mimicry (VM) refers to the capacity of certain cancer cells to form fluid-conducting structures within a tumor in an endothelial cell (EC)-free manner. Ever since its first report by Maniotis in 1999, the existence of VM has been an extremely contentious issue. The overwhelming consensus of the literature suggests that VM is frequently observed in highly aggressive tumors and correlates to lower patient survival. While the presence of VM

Indexed as

angiogenesisendothelialin vivo–in vitromodelvasculogenic mimicry (VM)

Identifiers

PMID31428573
PMCPMC6688045
OpenAlexW2957739743

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.