Evidence map›Paper›PMID 31438634›Full record

ReviewMicroorganisms2019

Microbiota and Immune-Mediated Skin Diseases-An Overview.

Adrian Catinean, Maria Adriana Neag, Andrei Otto Mitre, Corina Ioana Bocsan, Anca Dana Buzoianu

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Dysbiosis in the Pathogenesis of Atopic Dermatitis.The Journal of dermatology · 2026
    Review
  4. Review
  5. Article
  6. The Role of Skin Dysbiosis and Quorum Sensing in Atopic Dermatitis.JID innovations : skin science from molecules to population health · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Blueberry Supplementation and Skin Health.Antioxidants (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Treatment Options for Troublesome Itch.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Protein-Based Systems for Topical Antibacterial Therapy.Frontiers in medical technology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Adrian CatineanDepartment of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.
Maria Adriana NeagPharmacology, Toxicology and Clinical Pharmacology Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania. borosmeda@yahoo.com.
Andrei Otto MitreFaculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.ORCID 0000-0002-1121-4042
Corina Ioana BocsanPharmacology, Toxicology and Clinical Pharmacology Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.
Anca Dana BuzoianuPharmacology, Toxicology and Clinical Pharmacology Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, increased attention has been paid to the relationship between microbiota and various diseases, especially immune-mediated diseases. Because conventional therapy for many autoimmune diseases is limited both in efficacy and safety, there is an increased interest in identifying nutraceuticals, particularly probiotics, able to modulate the microbiota and ameliorate these diseases. In this review, we analyzed the research focused on the role of gut microbiota and skin in immunity, their role in immune-mediated skin diseases (IMSDs), and the beneficial effect of probiotics in patients with this pathology. We selected articles published between 2009 and 2019 in PubMed and ScienceDirect that provided information regarding microbiota, IMSDs and the role of probiotics in these diseases. We included results from different types of studies including observational and interventional clinical trials or in vivo and in vitro experimental studies. Our results showed that probiotics have a beneficial effect in changing the microbiota of patients with IMSDs; they also influence disease progression. Further studies are needed to better understand the impact of new therapies on intestinal microbiota. It is also important to determine whether the microbiota of patients with autoimmune diseases can be manipulated in order to restore homeostasis of the microbiota.

Indexed as

autoimmune skin diseasesimmune-mediated diseasesmicrobiotaprobiotics

Identifiers

PMID31438634
PMCPMC6781142
OpenAlexW2969356900

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.