ArticleACS biomaterials science & engineering2018
Fibroblasts: Diverse Cells Critical to Biomaterials Integration.
Article in ACS biomaterials science & engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Smart ROS-regulating biomimetic hydrogel promotes scarless diabetic wound healing via macrophage reprogramming.Materials today. Bio · 2026Article
- Evaluation of the remineralisation effect and biocompatibility of boron-doped bioactive glass material on artificial root surface caries.BMC oral health · 2025Article
- Stromagenesis and cancer-associated fibroblast heterogeneity in primary tumors and metastasis: focus in non-small cell lung cancer.FEBS open bio · 2025Review
- Combination of Polydopamine and Plasma Oxidation to Increase Tissue Integration of Polyurethane-Silicone Copolymers for Cardiovascular Implants.Advanced healthcare materials · 2025Article
- Next-Generation Biomaterials for Load-Bearing Tissue Interfaces: Sensor-Integrated Scaffolds and Mechanoadaptive Constructs for Skeletal Regeneration.Journal of functional biomaterials · 2025Review
- Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity.Biomaterials · 2025Article
- Multiscale computational model predicts how environmental changes and treatments affect microvascular remodeling in fibrotic disease.PNAS nexus · 2025Article
- Pore morphology of bijel-templated materials promotes migration and downregulates αSMA expression in human fibroblasts.Frontiers in bioengineering and biotechnology · 2025Article
- From laboratory to clinic: a precise treatment strategy of mesenchymal stem cells-derived exosomes pretreated by simulating disease microenvironment.Frontiers in immunology · 2025Review
- Article
- Improved Composite Hydrogel for Bioengineered Tracheal Graft Demonstrates Effective Early Angiogenesis.Journal of clinical medicine · 2024Article
- Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity.bioRxiv : the preprint server for biology · 2024Article
- Unraveling and Harnessing the Immune Response at the Cell-Biomaterial Interface for Tissue Engineering Purposes.Advanced healthcare materials · 2024Review
- Biocompatible adipose extracellular matrix and reduced graphene oxide nanocomposite for tissue engineering applications.Materials today. Bio · 2024Article
- Nanoparticles of Cerium-Doped Zeolitic Imidazolate Framework-8 Promote Soft Tissue Integration by Reprogramming the Metabolic Pathways of Macrophages.ACS biomaterials science & engineering · 2023Article
- Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration.Biomimetics (Basel, Switzerland) · 2023Review
- Polydopamine-assisted tranilast immobilization on a PLA chamber to enhance fat flaps regeneration by reducing tissue fibrosis.RSC advances · 2023Article
- Improving hard metal implant and soft tissue integration by modulating the "inflammatory-fibrous complex" response.Bioactive materials · 2023Article
- Modulating Myofibroblastic Differentiation of Fibroblasts through Actin-MRTF Signaling Axis by Micropatterned Surfaces for Suppressed Implant-Induced Fibrosis.Research (Washington, D.C.) · 2023Article
- Anisotropicity and flexibility in trilayered microfibrous substrates promote heart valve leaflet tissue engineering.Biomedical materials (Bristol, England) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Fibroblasts are key participants in wound healing and inflammation, and are capable of driving the progression of tissue repair to fully functional tissue or pathologic scar, or fibrosis, depending on the specific mechanical and biochemical cues with which they are presented. Thus, understanding and modulating the fibroblastic response to implanted materials is paramount to achieving desirable outcomes, such as long-term implant function or tissue regeneration. However, fibroblasts are remarkably heterogeneous and can differ vastly in their contributions to regeneration and fibrosis. This heterogeneity exists between tissues and within tissues, down to the level of individual cells. This review will discuss the role of fibroblasts, the pitfalls of describing them as a collective, the specifics of their function, and potential future directions to better understand and organize their highly variable biology.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.