Evidence map›Paper›PMID 31441503›Full record

ArticleJournal of neurochemistry2019

Does APC/C

Maike F Dohrn, Juan P Bolaños

Open access · hybridAbstract readEditorialComment
In one paragraph

Article in Journal of neurochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Maike F DohrnDepartment of Neurology, Medical Faculty, RWTH Aachen University, Aachen, Germany.ORCID 0000-0002-5320-9807
Juan P BolañosInstitute of Functional Biology and Genomics, CSIC, University of Salamanca, Salamanca, Spain.ORCID 0000-0002-3949-6862
RWTH Aachen University · DEUniversidad de Salamanca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This editorial highlights a study by Rodriguez, Sanchez-Moran et al. (2019) in the current issue of the Journal of Neurochemistry, in which the authors describe a microcephalic boy carrying the novel heterozygous de novo missense mutation c.560A> G; p.Asp187Gly in Cdh1/Fzr1 encoding the APC/C E3-ubiquitin ligase cofactor CDH1. A functional characterization of mutant APC/C

Indexed as

EpilepsyMicrocephalyAnaphaseAnaphase-Promoting Complex-CyclosomeAnimalsAntigens, CDCadherinsCdh1 ProteinsHumansMaleMiceMutationOrgan SizeAnaphase-Promoting Complex-CyclosomeAntigens, CDCadherinsCDH1 protein, humanCdh1 ProteinsFZR1 protein, human

Identifiers

PMID31441503
PMCPMC6851737
OpenAlexW2969781760

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.