Evidence map›Paper›PMID 31450674›Full record

ArticleCells2019

Somatic Mutations of

Zachary J Brandt, Paula N North, Brian A Link

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zachary J BrandtDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Paula N NorthDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Brian A LinkDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA. blink@mcw.edu.
Medical College of Wisconsin · US

Funding

RPE Signaling in Ocular Health and DiseaseR01EY029267 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI LINK, BRIAN A · 2018 to 2021
$1.8M
NEI NIH HHS R01 EY029267
6 · The paper itself

Abstract

The cellular signaling pathways underlying peripheral nerve sheath tumor (PNST) formation are poorly understood. Hippo signaling has been recently implicated in the biology of various cancers, and is thought to function downstream of mutations in the known PNST driver,

Indexed as

MutationAnimalsCell ProliferationCRISPR-Cas SystemsGene EditingHippo KinasesNeoplasms, ExperimentalNerve Sheath NeoplasmsProtein Serine-Threonine KinasesSerine-Threonine Kinase 3Signal TransductionZebrafishZebrafish ProteinsHippo Kinaseslats2 protein, zebrafishProtein Serine-Threonine KinasesSerine-Threonine Kinase 3stk3 protein, zebrafishZebrafish ProteinsHippoLats2peripheral nerve sheath tumorschwannomaTazYapzebrafish

Identifiers

PMID31450674
PMCPMC6770745
OpenAlexW2969767999

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.