Evidence map›Paper›PMID 31462142›Full record

ArticleCell cycle (Georgetown, Tex.)2019

Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells.

Fabrice Gonnot, Diana Langer, Pierre-Yves Bourillot, Nathalie Doerflinger, Pierre Savatier

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Coupling of stemness maintenance with cell cycle control in stem cells.Frontiers in cell and developmental biology · 2025
    Review
  2. Regulatory Role ofInternational journal of molecular sciences · 2024
    Article
  3. Review
  4. G1-phase progression in pluripotent stem cells.Cellular and molecular life sciences : CMLS · 2021
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fabrice GonnotStem Cell and Brain Research Institute, Univ Lyon, Université Lyon 1, Inserm , Bron , France.
Diana LangerStem Cell and Brain Research Institute, Univ Lyon, Université Lyon 1, Inserm , Bron , France.
Pierre-Yves BourillotStem Cell and Brain Research Institute, Univ Lyon, Université Lyon 1, Inserm , Bron , France.ORCID https://orcid.org/0000-0003-1657-8555
Nathalie DoerflingerStem Cell and Brain Research Institute, Univ Lyon, Université Lyon 1, Inserm , Bron , France.
Pierre SavatierStem Cell and Brain Research Institute, Univ Lyon, Université Lyon 1, Inserm , Bron , France.ORCID https://orcid.org/0000-0002-8944-9853
Université Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continuous, non-cell cycle-dependent expression of cyclin E is a characteristic feature of mouse embryonic stem cells (mESCs). We studied the 5' regulatory region of

Indexed as

Promoter Regions, GeneticAnimalsBinding SitesCell DifferentiationCell LineChromatin ImmunoprecipitationCyclin ECyclinsDNA-Binding ProteinsGene Knockdown TechniquesKruppel-Like Factor 4Kruppel-Like Transcription FactorsMiceMicroRNAsMouse Embryonic Stem CellsReceptors, EstrogenCcne2 protein, mouseCyclin ECyclinsDNA-Binding ProteinsEsrrb protein, mouseKlf4 protein, mouseKruppel-Like Factor 4Kruppel-Like Transcription FactorsMicroRNAsMirn15a microRNA, mouseReceptors, EstrogenRNA, Small InterferingTfcp2 protein, mouseTranscription Factorscell-cycleCyclin EEmbryonic stem cellpluripotent

Identifiers

PMID31462142
PMCPMC6773236
OpenAlexW2970789181

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.