Evidence map›Paper›PMID 31471975›Full record

Observational studyClinical cardiology2019

How do cardiologists select patients for dual antiplatelet therapy continuation beyond 1 year after a myocardial infarction? Insights from the EYESHOT Post-MI Study.

Leonardo De Luca, Furio Colivicchi, Jennifer Meessen, Massimo Uguccioni, Federico Piscione, Paola Bernabò, Gerardina Lardieri, Antonino Granatelli, Domenico Gabrielli, Michele M Gulizia and 1 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Leonardo De LucaDivision of Cardiology, S. Giovanni Evangelista Hospital, Tivoli, Italy.ORCID https://orcid.org/0000-0002-8552-1272
Furio ColivicchiDivision of Cardiology, S. Filippo Neri Hospital, Rome, Italy.
Jennifer MeessenDepartment of Cardiovascular Research, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Massimo UguccioniDivision of Cardiology, Azienda Ospedaliera S. Camillo-Forlanini, Rome, Italy.
Federico PiscioneDivision of Preventive Cardiology, SS Giovanni di Dio e Ruggi d'Aragona Hospital, University of Salerno, Fisciano, Italy.
Paola BernabòDivision of Cardiology, Ospedali Galliera, Genoa, Italy.
Gerardina LardieriDivision of Cardiology, Ospedale di Gorizia e Monfalcone, Monfalcone, Salerno, Italy.
Antonino GranatelliDivision of Cardiology, S. Giovanni Evangelista Hospital, Tivoli, Italy.
Domenico GabrielliDivision of Cardiology, Augusto Murri Hospital, Fermo, Italy.
Michele M GuliziaDivision of Cardiology, Garibaldi-Nesima Hospital, Catania, Italy.
EYESHOT Post-MI Investigators
Ospedale Maggiore · ITAzienda Ospedaliera San Camillo-Forlanini · ITEnte Ospedaliero Ospedali Galliera · ITMario Negri Institute for Pharmacological Research · ITOspedale di Monfalcone · ITOspedale Garibaldi · ITOspedale San Filippo Neri · ITTrinity Hospital of Augusta · USUniversity of Salerno · IT

Funding

Heart Care Foundation
6 · The paper itself

Abstract

backgroundCurrent guidelines suggest to consider dual antiplatelet therapy (DAPT) continuation for longer than 12 months in selected patients with myocardial infarction (MI). HYPOTHESIS: We sought to assess the criteria used by cardiologists in daily practice to select patients with a history of MI eligible for DAPT continuation beyond 1 year.

methodsWe analyzed data from the EYESHOT Post-MI, a prospective, observational, nationwide study aimed to evaluate the management of patients presenting to cardiologists 1 to 3 years from the last MI event.

resultsOut of the 1633 post-MI patients enrolled in the study between March and December 2017, 557 (34.1%) were on DAPT at the time of enrolment, and 450 (27.6%) were prescribed DAPT after cardiologist assessment. At multivariate analyses, a percutaneous coronary intervention (PCI) with multiple stents and the presence of peripheral artery disease (PAD) resulted as independent predictors of DAPT continuation, while atrial fibrillation was the only independent predictor of DAPT interruption for patients both at the second and the third year from MI at enrolment and the time of discharge/end of the visit.

conclusionsRisk scores recommended by current guidelines for guiding decisions on DAPT duration are underused and misused in clinical practice. A PCI with multiple stents and a history of PAD resulted as the clinical variables more frequently associated with DAPT continuation beyond 1 year from the index MI.

Indexed as

CardiologistsPatient SelectionRegistriesAgedAspirinClopidogrelDrug Administration ScheduleDual Anti-Platelet TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsProspective StudiesAspirinClopidogrelPlatelet Aggregation Inhibitorsclopidogreldual antiplatelet therapypercutaneous coronary interventionpost-MIsecondary preventionticagrelor

Identifiers

PMID31471975
PMCPMC6837024
OpenAlexW2971090230

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.