Evidence map›Paper›PMID 31475864›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2019

δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis.

Li Liu, Xingguo Zhu, Alexander Yu, Christina M Ward, Betty S Pace

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Li LiuDepartment of Biological Sciences, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID 0000-0001-6619-4133
Xingguo ZhuDepartment of Pediatrics, Augusta University, Augusta, GA 30912, USA.
Alexander YuDepartment of Medicine, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA, United States.
Christina M WardDepartment of Biochemistry and Molecular Biology, Boston University, Boston, MA 02118, USA.
Betty S PaceDepartment of Pediatrics, Augusta University, Augusta, GA 30912, USA.
Augusta University · USBoston University · USThe University of Texas at Dallas · US

Funding

Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3M
Mechanisms For p38 MAP Kinase DependentT Gene InductionR01HL069234 · NHLBI · UNIVERSITY OF TEXAS DALLAS · PI PACE, BETTY SUE · 2001 to 2017
$4.6M
NHLBI NIH HHS R01 HL069234NHLBI NIH HHS T32 HL007224
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aminolevulinic AcidBiosynthetic PathwaysCell LineErythroid Precursor CellsFetal Hemoglobingamma-GlobinsGene Expression RegulationHemeHumansModels, BiologicalNF-E2-Related Factor 2Promoter Regions, GeneticProtein BindingReactive Oxygen SpeciesAminolevulinic AcidFetal Hemoglobingamma-GlobinsHemeNFE2L2 protein, humanNF-E2-Related Factor 2Reactive Oxygen Speciesfetal hemoglobinglobin expressionheme biosynthesisNRF2reactive oxygen speciesδ-Aminolevulinate

Identifiers

PMID31475864
PMCPMC6802153
OpenAlexW2971336387

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.