Evidence map›Paper›PMID 31480361›Full record

ArticleGenes2019

Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers.

Bryan R Helm, Xiaohui Zhan, Pankita H Pandya, Mary E Murray, Karen E Pollok, Jamie L Renbarger, Michael J Ferguson, Zhi Han, Dong Ni, Jie Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Bryan R HelmDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.ORCID 0000-0003-3386-7842
Xiaohui ZhanDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.ORCID 0000-0003-1326-6601
Pankita H PandyaDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.
Mary E MurrayDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.
Karen E PollokDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.
Jamie L RenbargerDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.
Michael J FergusonDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.
Zhi HanDepartment of Pharmacology and Toxicology, Indiana University, Indianapolis, IN 46202-3082, USA.
Dong NiNational-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Jie ZhangDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA. jizhan@iu.edu.
Kun HuangDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA. kunhuang@iu.edu.
Indiana University School of MedicineShenzhen University Health Science Center · CNIndiana University – Purdue University Indianapolis · USRegenstrief Institute · US

Funding

Project 2: Biomarkers of endothelial dysfunction in pediatric patients receiving high intensity chemotherapy/irradiationU54HD090215 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI RENBARGER, JAMIE L · 2016 to 2018
$2.3M
Informatics Links Between Histological Features and Genetics in CancerU01CA188547 · NCI · OHIO STATE UNIVERSITY · PI HUANG, KUN · 2015 to 2017
$1.2M
NCI NIH HHS U01 CA188547NICHD NIH HHS U54 HD090215
6 · The paper itself

Abstract

Rhabdomyosarcoma is subclassified by the presence or absence of a recurrent chromosome translocation that fuses the

Indexed as

Gene Expression Regulation, NeoplasticGene Regulatory NetworksHumansOncogene Proteins, FusionPaired Box Transcription FactorsRhabdomyosarcomaRNA, MessengerTranscriptomeOncogene Proteins, FusionPaired Box Transcription FactorsPAX3-FOXO1A fusion protein, humanPAX7-FOXO1A fusion protein, humanRNA, Messengercopy number variationgene co-expression analysisgene fusionquasi-clique mergerrhabdomyosarcoma

Identifiers

PMID31480361
PMCPMC6770752
OpenAlexW2970128476

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.