Evidence map›Paper›PMID 31487962›Full record

ArticleCancers2019

The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach.

Sara Rezzola, Roberto Ronca, Alessandra Loda, Mohd Imtiaz Nawaz, Chiara Tobia, Giuseppe Paganini, Federica Maccarinelli, Arianna Giacomini, Francesco Semeraro, Marco Mor and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Role of long pentraxin PTX3 in cancer.Clinical and experimental medicine · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Differences Between Sorafenib and Lenvatinib Treatment from Genetic and Clinical Perspectives for Patients with Hepatocellular Carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Uveal Melanoma.Cancers · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sara RezzolaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy. sara.rezzola@unibs.it.
Roberto RoncaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Alessandra LodaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Mohd Imtiaz NawazDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Chiara TobiaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Giuseppe PaganiniDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Federica MaccarinelliDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Arianna GiacominiDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Francesco SemeraroEye Clinic, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy.
Marco MorDepartment of Food and Drug, University of Parma, 43125 Parma, Italy.
Marco PrestaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy. marco.presta@unibs.it.
University of Brescia · ITUniversity of Parma · IT

Funding

Associazione Italiana per la Ricerca sul Cancro IG grant n° 18943Associazione Italiana per la Ricerca sul Cancro MFAG grant n° 18459
6 · The paper itself

Abstract

Fibroblast growth factors (FGFs) play non-redundant autocrine/paracrine functions in various human cancers. The Cancer Genome Atlas (TCGA) data mining indicates that high levels of FGF and/or FGF receptor (FGFR) expression are associated with reduced overall survival, chromosome 3 monosomy and

Indexed as

FGFFGF receptorsliver metastasistumor graftsuveal melanomazebrafish

Identifiers

PMID31487962
PMCPMC6770058
OpenAlexW2971548050

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.