Evidence map›Paper›PMID 31488722›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Genetic dissection of active forgetting in labile and consolidated memories in

Yang Gao, Yichun Shuai, Xuchen Zhang, Yuwei Peng, Lianzhang Wang, Jing He, Yi Zhong, Qian Li

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Disruption of a selective vesicle pool upon retrograde amnesia dissociates memory at presynaptic terminals.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. Neuronal Actin Remodeling and Its Role in Higher Nervous Activity.International journal of molecular sciences · 2025
    Review
  5. What could evolve in the evolution of memory?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  6. Review
  7. Article
  8. Differential second messenger signaling via dopamine neurons bidirectionally regulates memory retention.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Anesthesia Resistant Memories in Drosophila, a Working Perspective.International journal of molecular sciences · 2022
    Review
  15. Article
  16. Social experiences switch states of memory engrams through regulating hippocampal Rac1 activity.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yang GaoTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Yichun ShuaiJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147.
Xuchen ZhangTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Yuwei PengTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Lianzhang WangTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Jing HeTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China.
Yi ZhongTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China; zhongyi@tsinghua.edu.cn liqian8@tsinghua.edu.cn.
Qian LiTsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, Ministry of Education Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, 100084 Beijing, China; zhongyi@tsinghua.edu.cn liqian8@tsinghua.edu.cn.
Tsinghua University · CNCenter for Life Sciences · CNHoward Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different memory components are forgotten through distinct molecular mechanisms. In

Indexed as

Actin-Related Protein 2-3 ComplexAnimalscdc42 GTP-Binding ProteinDrosophilaMemoryMemory ConsolidationMicrofilament ProteinsMushroom Bodiesrac1 GTP-Binding Proteinrho GTP-Binding ProteinsSignal TransductionWiskott-Aldrich Syndrome Protein FamilyActin-Related Protein 2-3 Complexcdc42 GTP-Binding ProteinMicrofilament Proteinsrac1 GTP-Binding Proteinrho GTP-Binding ProteinsWiskott-Aldrich Syndrome Protein FamilyactinDrosophilaforgettingmemoryRho GTPases

Identifiers

PMID31488722
PMCPMC6800343
OpenAlexW2971921130

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.