Evidence map›Paper›PMID 31504439›Full record

GuidelineEuropean heart journal2020

2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes.

Juhani Knuuti, William Wijns, Antti Saraste, Davide Capodanno, Emanuele Barbato, Christian Funck-Brentano, Eva Prescott, Robert F Storey, Christi Deaton, Thomas Cuisset and 16 more

Erratum issued 26 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 26 registered trials, which are not on this map. Cited by 3,291 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3,291citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05998525 phase3completedstarted 2021, after this paper: background citation

Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography

Ran2021Enrolled54Registered outcomes6Posted comparisons0ConditionsDiabetes Mellitus, Type 2, Diabete Type 2, Myocardial Infarction, Unstable AnginaArmsDapagliflozin 10mg Tab, Placebo
PMID 33303068PMID 26606676PMID 11239408PMID 25937196other papers from this trial
Open the trial in the graph
NCT04388280 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Functional and Anatomic Imaging Versus No Testing in Asymptomatic High-risk Diabetic Patients

TypeinterventionalSponsorClinical Centre of SerbiaRan2021 to 2023Enrolled400ConditionsAsymptomatic, High Risk, DiabetesArmsEchocardiography, CT angiography
NCT04424121 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Cardiac CT, Calcium Scoring and ECG Stress Testing in Patients With Suspected Coronary Artery Disease: Precision Phenotyping and Financial Evaluation (The DATASET-PRECISE Randomized Trial)

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2021 to 2023Enrolled900ConditionsStable Angina, Coronary Artery Disease, Atherosclerosis, Coronary Artery CalcificationArmsCCTA
NCT04674449 narecruitingnot on this map

International Study of Coronary Microvascular Angina (iCorMicA): a Randomised, Controlled, Multicentre Trial and Registry

TypeinterventionalSponsorNHS Greater Glasgow and ClydeRan2020 to 2030Enrolled1,500ConditionsMicrovascular Angina, Angina, Stable, Ischemia With No Obstructive Coronary Arteries (INOCA), Coronary Microvascular Dysfunction (CMD)ArmsDisclosure of IDP results, IDP performed but results not disclosed
NCT04675073 phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

Preventive VT Substrate Ablation in Patients With Chronic Post-MI Scar Showing Arrhythmogenic Characteristics

TypeinterventionalSponsorCentro Medico TeknonRan2021 to 2025Enrolled58ConditionsVentricular Tachycardia, Ventricular Arrythmia, Sudden Cardiac Death, Sudden Cardiac Death Due to Cardiac ArrhythmiaArmsVentricular tachycardia substrate-based radiofrequency ablation
NCT04857762 unknown statusnot on this mapstarted 2021, after this paper: background citation

Anatomical Assessment Versus Pull Back REsting Full-cycle rAtio (RFR) Measurement for Evaluation of Focal and Diffuse Coronary Disease

Typeobservational_patient_registrySponsorSzabolcs - Szatmár - Bereg County Hospitals and University Teaching Hospital, András Jósa Teaching HRan2021 to 2024Enrolled500ConditionsCoronary Artery Stenosis
NCT04885816 naterminatednot on this mapstarted 2021, after this paper: background citation

Drug-Eluting Balloon Versus Drug-eluting Stent On de Novo coRonary Artery Disease in Patients With High Bleeding Risk

TypeinterventionalSponsorInstituto Nacional de Cardiologia Ignacio ChavezRan2021 to 2021Enrolled5ConditionsHigh Bleeding Risk, Coronary Artery Disease (CAD), Percutaneous Coronary Intervention (PCI)ArmsDrug Eluting Balloon (DEB), Drug Eluting Stents (DES)
NCT04907786 unknown statusnot on this mapstarted 2021, after this paper: background citation

Coronary Computed Tomography Angiography Guidance in Invasive Coronary Angiography; a Prospective Registry Study

Typeobservational_patient_registrySponsorCatharina Ziekenhuis EindhovenRan2021 to 2022Enrolled250ConditionsCoronary Artery Disease
NCT04975425 completednot on this mapstarted 2021, after this paper: background citation

Effects of Guiding Catheter on Fractional Flow Reserve and Non-Hyperemic Pressure Ratios for the Assessment of Coronary Artery Stenoses - Disengage @Rest

TypeobservationalSponsorFederico II UniversityRan2021 to 2022Enrolled200ConditionsCoronary Artery DiseaseArmsFractional Flow Reserve
NCT04977089 unknown statusnot on this map

Study of Lipid Profile of Patients With Chronic Coronary Syndromes at Sohag University Hospital

TypeobservationalSponsorSohag UniversityRan2020 to 2021Enrolled100ConditionsIschemic Heart Disease, DyslipidemiasArmslipid profile test .
NCT04990791 phase4completednot on this mapstarted 2021, after this paper: background citation

Characterisation of a Novel Regimen of Very Low-dose Aspirin Combined With Rivaroxaban in Patients With Chronic Coronary Syndromes: WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?

TypeinterventionalSponsorSheffield Teaching Hospitals NHS Foundation TrustRan2021 to 2023Enrolled48ConditionsCoronary SyndromeArmsAspirin 75mg, Aspirin 20mg, Rivaroxaban 2.5 mg
NCT05261464 phase4unknown statusnot on this mapstarted 2021, after this paper: background citation

Heart Rate Controller in Computed Tomography Coronary Angiography: A Randomized Controlled Trial of Metoprolol, Diltiazem and Ivabradine

TypeinterventionalSponsorMahidol UniversityRan2021 to 2022Enrolled246ConditionsHeart Rate, Coronary Computed Tomography AngiographyArmsMetoprolol tartrate, Ivabradine, Diltiazem
NCT05369728 nanot yet recruitingnot on this mapstarted 2022, after this paper: background citation

Medico-economic Evaluation of a Strategy With Coronary CT as First Line (CCTA) Compared With the Strategy With Functional Test as First Line, in Patients at Intermediate Risk of Developing Stable Coronary Disease.

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2022 to 2026Enrolled800ConditionsCardiology, Coronary Artery DiseaseArmsCoronary CT in 1st line compared to the strategy with functional test in 1st line in patient at Intermediate Risk of Developing Stable Coronary Disease:
NCT05698732 recruitingnot on this mapstarted 2023, after this paper: background citation

Coroflex® ISAR NEO Coronary Stent System Post-Market Clinical Follow-up Study

TypeobservationalSponsorFundación EPICRan2023 to 2027Enrolled3,000ConditionsCoronary Artery Disease (CAD), Ischemic Heart DiseaseArmsCoroflex® ISAR NEO coronary stent system
NCT05714241 recruitingnot on this mapstarted 2022, after this paper: background citation

BIOmarkers and PLAtelet Function Assessment in Myocardial Ischemia and Non Obstructive Coronary Arteries Study: The BIOplatINO Study

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2022 to 2027Enrolled200ConditionsIschemia With no Obstructive Coronary Artery DiseaseArmsData extraction, Blood sampling, Clinical Follow-up
NCT05714319 recruitingnot on this mapstarted 2023, after this paper: background citation

Intracoronary Provocative Test With Acetylcholine in Patients With Stable Myocardial Ischemia or Myocardial Infarction and Non-Obstructive Coronary Arteries: the "Provoke" Study

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2023 to 2028Enrolled600ConditionsMyocardial Infarction With Non-Obstructive Coronary Artery, Ischemia With Non-Obstructive Coronary ArteryArmsData collection, Clinical follow-up
NCT05721170 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Impact of Beta-blockers Among Patients Undergoing TAVI: a Randomized Multicenter Trial

TypeinterventionalSponsorNational and Kapodistrian University of AthensRan2024 to 2028Enrolled347ConditionsAortic Valve StenosisArmsBeta blocker
NCT05760157 unknown statusnot on this mapstarted 2023, after this paper: background citation

To Establish a Multimodal Dynamic Risk Assessment System of Heart Failure in Patients With Myocardial Infarction Based on Coronary Microcirculation.

TypeobservationalSponsorJian LiuRan2023 to 2025Enrolled567ConditionsHeart Failure, Acute Myocardial InfarctionArmsPossible risk factors of heart failure
NCT05782582 narecruitingnot on this mapstarted 2023, after this paper: background citation

Chronic Coronary Syndrome in Swedish Primary Care

TypeinterventionalSponsorRegion ÖstergötlandRan2023 to 2032Enrolled500ConditionsCoronary Artery DiseaseArmsPackage investigation, Sound registration with Cadscore® and added risk calculation, Standard investigation
NCT05860400 recruitingnot on this mapstarted 2023, after this paper: background citation

Efficacy and Safety of Comprehensive Treatment in Patients With Inflammation-associated Rapidly-progressive Coronary Artery Disease (IR-CAD): a Self-controlled Cohort Study

Typeobservational_patient_registrySponsorPeking Union Medical College HospitalRan2023 to 2026Enrolled39ConditionsCoronary Artery Disease, Coronary Artery Stenosis, Coronary Artery Restenosis, Coronary Artery Disease ProgressionArmsHealthy life style, Secondary prevention for atherosclerotic coronary artery disease, Immunosuppressive therapy, Coronary revascularization, Supportive therapies
NCT06007248 recruitingnot on this mapstarted 2023, after this paper: background citation

Disease Characteristics of Inflammation-associated Rapidly-progressive Coronary Artery Disease (IR-CAD): a Case-control Study

TypeobservationalSponsorPeking Union Medical College HospitalRan2023 to 2026Enrolled30ConditionsCoronary Artery Disease, Coronary Artery Stenosis, Coronary Artery Restenosis, Coronary Artery Disease ProgressionArmsProtocol-defined Examinations
NCT06029387 completednot on this mapstarted 2023, after this paper: background citation

Artificial Intelligence for Preventing Heart Disease: Observational, Single Center, Prospective and Retrospective Study

TypeobservationalSponsorIRCCS San RaffaeleRan2023 to 2024Enrolled3,000ConditionsCoronary Artery Disease
NCT06306066 completednot on this map

Coronary Microvascular Dysfunction in Chronic Coronary Syndrome - Invasive Assessment With Thermo-dilution Technique in the LAD and Biobanking in an All-comer Population

TypeobservationalSponsorKarolinska InstitutetRan2015 to 2022Enrolled505ConditionsCoronary Artery Disease, Microvascular Angina, Coronary Microvascular Dysfunction
NCT06577038 enrolling by invitationnot on this map

Prospective, International, Multicenter, All-comers Registry for the Study of Intravascular Lithotripsy in Coronary Interventions

Typeobservational_patient_registrySponsorLeiden University Medical CenterRan2019 to 2029Enrolled1,000ConditionsCalcific Coronary ArteriosclerosisArmsPCI with use of IVL
NCT06896903 narecruitingnot on this mapstarted 2025, after this paper: background citation

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

TypeinterventionalSponsorBaylor Research InstituteRan2025 to 2027Enrolled50ConditionsANOCA - Angina With Non-obstructive Coronary Arteries, INOCA (Ischemia With Non Obstructive Coronary Artery Disease)ArmsCoronary reactivity testing with and without nitrates
NCT07315399 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Correlation Between Obstructive Sleep Apnea-Related Nocturnal Hypoxemia Parameters and Coronary Microvascular Dysfunction: A Prospective Cohort Study

Typeobservational_patient_registrySponsorBeijing Anzhen HospitalRan2025 to 2030Enrolled560ConditionsOSA - Obstructive Sleep Apnea, Coronary Microvascular Dysfunction (CMD), Coronary Artery Disease (CAD)ArmsPolysomnography
3 · Its place in the literature

Who cites it

3,291 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  6. Trial
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  18. Repositioning of exercise treadmill testing in contemporary chest pain management.The international journal of cardiovascular imaging · 2026
    Review
  19. Article
  20. Article

3,231 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors.

Juhani Knuuti
William Wijns
Antti Saraste
Davide Capodanno
Emanuele Barbato
Christian Funck-Brentano
Eva Prescott
Robert F Storey
Christi Deaton
Thomas Cuisset
Stefan Agewall
Kenneth Dickstein
Thor Edvardsen
Javier Escaned
Bernard J Gersh
Pavel Svitil
Martine Gilard
David Hasdai
Robert Hatala
Felix Mahfoud
Josep Masip
Claudio Muneretto
Marco Valgimigli
Stephan Achenbach
Jeroen J Bax
ESC Scientific Document Group

Funding

British Heart Foundation PG/17/25/32884
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiologyDiagnostic Techniques, CardiovascularDisease ManagementSocieties, MedicalChronic DiseaseCoronary Artery DiseaseEuropeHumansSyndromeangina pectorisanti-ischaemic drugsantithrombotic therapychronic coronary syndromescoronary artery diseasediagnostic testingGuidelinesimaginglifestyle modificationslipid-lowering drugsmicrovascular anginamyocardial ischaemiamyocardial revascularizationrisk assessmentscreeningvasospastic angina

Identifiers

PMID31504439

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 20 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.