Evidence map›Paper›PMID 31508827›Full record

ArticleMedical physics2019

Body motion detection and correction in cardiac PET: Phantom and human studies.

Tao Sun, Yoann Petibon, Paul K Han, Chao Ma, Sally J W Kim, Nathaniel M Alpert, Georges El Fakhri, Jinsong Ouyang

Abstract read
In one paragraph

Article in Medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Effects of List-Mode-Based Intraframe Motion Correction in Dynamic Brain PET Imaging.IEEE transactions on radiation and plasma medical sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impact of motion correction on [Physics in medicine and biology · 2023
    Article
  9. Inter-pass motion correction for whole-body dynamic PET and parametric imaging.IEEE transactions on radiation and plasma medical sciences · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Synergistic motion compensation strategies for positron emission tomography when acquired simultaneously with magnetic resonance imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tao SunGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Yoann PetibonGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Paul K HanGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Chao MaGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Sally J W KimGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Nathaniel M AlpertGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Georges El FakhriGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Jinsong OuyangGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA.

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
PET/MR Mapping of Myocardial Membrane PotentialR01HL137230 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2017 to 2020
$3.3M
Quantitative Simultaneous Cardiac PET-MRR01HL118261 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI OUYANG, JINSONG · 2014 to 2018
$2.6M
National Institute of Health P41-EB022544National Institute of Health R01-HL118261National Institute of Health R01-HL137230National Institute of Health T32-EB013180NHLBI NIH HHS R01 HL118261NHLBI NIH HHS R01 HL137230NIBIB NIH HHS P41 EB022544NIBIB NIH HHS T32 EB013180
6 · The paper itself

Abstract

purposePatient body motion during a cardiac positron emission tomography (PET) scan can severely degrade image quality. We propose and evaluate a novel method to detect, estimate, and correct body motion in cardiac PET.

methodsOur method consists of three key components: motion detection, motion estimation, and motion-compensated image reconstruction. For motion detection, we first divide PET list-mode data into 1-s bins and compute the center of mass (COM) of the coincidences' distribution in each bin. We then compute the covariance matrix within a 25-s sliding window over the COM signals inside the window. The sum of the eigenvalues of the covariance matrix is used to separate the list-mode data into "static" (i.e., body motion free) and "moving" (i.e. contaminated by body motion) frames. Each moving frame is further divided into a number of evenly spaced sub-frames (referred to as "sub-moving" frames), in which motion is assumed to be negligible. For motion estimation, we first reconstruct the data in each static and sub-moving frame using a rapid back-projection technique. We then select the longest static frame as the reference frame and estimate elastic motion transformations to the reference frame from all other static and sub-moving frames using nonrigid registration. For motion-compensated image reconstruction, we reconstruct all the list-mode data into a single image volume in the reference frame by incorporating the estimated motion transformations in the PET system matrix. We evaluated the performance of our approach in both phantom and human studies.

resultsVisually, the motion-corrected (MC) PET images obtained using the proposed method have better quality and fewer motion artifacts than the images reconstructed without motion correction (NMC). Quantitative analysis indicates that MC yields higher myocardium to blood pool concentration ratios. MC also yields sharper myocardium than NMC.

conclusionsThe proposed body motion correction method improves image quality of cardiac PET.

Indexed as

MovementPhantoms, ImagingArtifactsFluorodeoxyglucose F18HeartHumansImage Processing, Computer-AssistedPositron-Emission TomographyFluorodeoxyglucose F18body motionbulk motioncardiac PETimage reconstructionmotion correctionmotion detectionmotion estimation

Identifiers

PMID31508827
PMCPMC6842053

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.