Evidence map›Paper›PMID 31520895›Full record

ArticleAmerican heart journal2019

Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise (CardioRACE): Rationale, design, and methods.

Angelique G Brellenthin, Lorraine M Lanningham-Foster, Marian L Kohut, Yehua Li, Timothy S Church, Steven N Blair, Duck-Chul Lee

Open access · greenAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in American heart journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  16. Role of Resistance Exercise in Cardiology.Anatolian journal of cardiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Angelique G BrellenthinDepartment of Kinesiology, Iowa State University, Ames, IA.
Lorraine M Lanningham-FosterDepartment of Food Science and Human Nutrition, Iowa State University, Ames, IA.
Marian L KohutDepartment of Kinesiology, Iowa State University, Ames, IA.
Yehua LiDepartment of Statistics, University of California-Riverside, Riverside, CA.
Timothy S ChurchDepartment of Preventive Medicine, Pennington Biomedical Research Center, Baton Rouge, LA.
Steven N BlairDepartment of Exercise Science, University of South Carolina, Columbia, SC.
Duck-Chul LeeDepartment of Kinesiology, Iowa State University, Ames, IA. Electronic address: dclee@iastate.edu.
Iowa State University · USPennington Biomedical Research Center · USUniversity of California, Riverside · USUniversity of South Carolina · US

Funding

Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise (Cardio-RACE)R01HL133069 · NHLBI · IOWA STATE UNIVERSITY · PI LEE, DUCK-CHUL · 2016 to 2020
$3.4M
NHLBI NIH HHS R01 HL133069
6 · The paper itself

Abstract

backgroundThe benefits of aerobic exercise (AE) for cardiovascular disease (CVD) have been well documented. Resistance exercise (RE) has been traditionally examined for its effects on bone density, physical function, or metabolic health, yet few data exist regarding the benefits of RE, independent of and combined with AE, for CVD prevention. This randomized controlled trial, "Comparison of the Cardiovascular Benefits of Resistance, Aerobic, and Combined Exercise (CardioRACE)," is designed to determine the relative benefits of RE, AE, or combined RE plus AE training on CVD risk factors.

methodsParticipants are 406 inactive men and women (35-70 years) with a body mass index of 25-40 kg/m

resultsThe primary outcome is a composite z score including resting BP, low-density lipoprotein cholesterol (LDL-C), fasting glucose, and percent body fat, which is assessed at baseline, 6 months, and 12 months. Diet and outside physical activity are measured throughout the intervention for 1 year.

conclusionCardioRACE (ClinicalTrials.govNCT03069092) will fill an important knowledge gap regarding the effects of RE, alone or in addition to the well-documented effects of AE. CardioRACE will help generate more comprehensive and synergistic clinical and public health strategies to prevent CVD.

Indexed as

AdultAgedBlood PressureBody Mass IndexCardiovascular DiseasesCombined Modality TherapyExerciseExercise TherapyFemaleHumansLipoproteins, LDLMaleMiddle AgedPatient CompliancePatient SelectionRandomized Controlled Trials as TopicLipoproteins, LDL

Identifiers

PMID31520895
PMCPMC6861681
OpenAlexW2967703244

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.