Evidence map›Paper›PMID 31521114›Full record

ArticleBMC family practice2019

Adherence to treatment and related factors among patients with chronic conditions in primary care: a cross-sectional study.

Cesar I Fernandez-Lazaro, Juan M García-González, David P Adams, Diego Fernandez-Lazaro, Juan Mielgo-Ayuso, Alberto Caballero-Garcia, Francisca Moreno Racionero, Alfredo Córdova, Jose A Miron-Canelo

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In one paragraph

Article in BMC family practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  16. Check the Impact of Mobile Health on Medication Adherence in Adolescents with Leukemia.Asian Pacific journal of cancer prevention : APJCP · 2025
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92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cesar I Fernandez-LazaroDepartment of Biomedical and Diagnostic Sciences, School of Medicine, University of Salamanca, Calle Alfonso X el Sabio s/n, 37007, Salamanca, Spain. fernandezlazaro@usal.es.ORCID 0000-0003-2366-2528
Juan M García-GonzálezDepartment of Sociology, Pablo de Olavide University, Seville, Spain.
David P AdamsDual Enrollment Program, Point University-Savannah Campus, Savannah, GA, USA.
Diego Fernandez-LazaroDepartment of Cell Biology, Histology and Pharmacology, University of Valladolid, Soria, Spain.
Juan Mielgo-AyusoDepartment of Biochemistry, Molecular Biology and Physiology, Faculty of Physical Therapy, University of Valladolid, Soria, Spain.
Alberto Caballero-GarciaDepartment of Anatomy and Radiology, University of Valladolid, Soria, Spain.
Francisca Moreno RacioneroCastile and Leon Healthcare Services, Valladolid, Spain.
Alfredo CórdovaDepartment of Biochemistry, Molecular Biology and Physiology, Faculty of Physical Therapy, University of Valladolid, Soria, Spain.
Jose A Miron-CaneloDepartment of Biomedical and Diagnostic Sciences, School of Medicine, University of Salamanca, Calle Alfonso X el Sabio s/n, 37007, Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence to treatment, a public health issue, is of particular importance in chronic disease therapies. Primary care practices offer ideal venues for the effective care and management of these conditions. The aim of this study is to assess adherence to treatment and related-factors among patients with chronic conditions in primary care settings.

methodsA cross-sectional study was conducted among 299 adult patients with ≥1 chronic condition(s) and prescribed medication in primary healthcare centers of Spain. The Morisky-Green-Levine questionnaire was used to assess medication adherence via face-to-face interviews. Crude and adjusted multivariable logistic regression models were used to analyze factors associated with adherence using the Multidimensional Model proposed by the World Health Organization - social and economic, healthcare team and system-related, condition-related, therapy-related, and patient-related factors.

resultsThe proportion of adherent patients to treatment was 55.5%. Older age (adjusted odds ratio 1.31 per 10-year increment, 95% CI 1.01-1.70), lower number of pharmacies used for medication refills (0.65, 95% CI 0.47-0.90), having received complete treatment information (3.89, 95% CI 2.09-7.21), having adequate knowledge about medication regimen (4.17, 95% CI 2.23-7.80), and self-perception of a good quality of life (2.17, 95% CI 1.18-4.02) were independent factors associated with adherence.

conclusionsAdherence to treatment for chronic conditions remained low in primary care. Optimal achievement of appropriate levels of adherence through tailored multifaceted interventions will require attention to the multidimensional factors found in this study, particularly those related to patients' education and their information needs.

Indexed as

Drug MonitoringAgedChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrimary Health CareSocioeconomic FactorsSpainSurveys and QuestionnairesChronic conditionsMedication adherenceMultidimensional factorsPatient adherencePatient educationPrimary careTreatment adherenceWHO multidimensional framework

Identifiers

PMID31521114
PMCPMC6744672

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.