Evidence map›Paper›PMID 31533971›Full record

ArticleJournal of cell science2019

Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle.

Battuya Bayarmagnai, Louisiane Perrin, Kamyar Esmaeili Pourfarhangi, Xavier Graña, Erkan Tüzel, Bojana Gligorijevic

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  7. Hydrogel Design to Understand and Guide 3D Cell Migration.Regenerative engineering and translational medicine · 2025
    Review
  8. Article
  9. Leader Cells: Invade and Evade-The Frontline of Cancer Progression.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Multiphoton intravital microscopy of rodents.Nature reviews. Methods primers · 2022
    Article
  20. Imaging developmental cell cycles.Biophysical journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Battuya BayarmagnaiDepartment of Bioengineering, Temple University, Philadelphia, PA 19122, USA.
Louisiane PerrinDepartment of Bioengineering, Temple University, Philadelphia, PA 19122, USA.
Kamyar Esmaeili PourfarhangiDepartment of Bioengineering, Temple University, Philadelphia, PA 19122, USA.
Xavier GrañaCancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Erkan TüzelDepartment of Bioengineering, Temple University, Philadelphia, PA 19122, USA.ORCID 0000-0002-1337-9932
Bojana GligorijevicDepartment of Bioengineering, Temple University, Philadelphia, PA 19122, USA bojana.gligorijevic@temple.edu.ORCID 0000-0001-9071-7467
Temple University · USFox Chase Cancer Center · US

Funding

Targeting invadopodia-related mechanisms of cancer cell invasion and metastasisR01CA230777 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI GLIGORIJEVIC, BOJANA · 2019 to 2023
$1.9M
Unraveling the complexity of substrate specificity of PP2A/B55a, a major eukaryote Serine/Threonine PhosphataseR01GM117437 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI GRANA, XAVIER · 2016 to 2019
$1.3M
Multimotor Mechanisms in Microtubule-based TransportR01GM121679 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI HANCOCK, WILLIAM OLAF · 2017 to 2020
$1.3M
Systems Microscopy Analysis of Tumor Cell Motility in Microenvironment ContextR00CA172360 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI GLIGORIJEVIC, BOJANA · 2015 to 2017
$747k
PPP2R2A tumor suppression haploinsufficiency in prostate cancerR03CA216134 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI GRANA, XAVIER · 2017 to 2018
$159k
NCI NIH HHS R00 CA172360NCI NIH HHS R01 CA230777NCI NIH HHS R03 CA216134NIGMS NIH HHS R01 GM117437NIGMS NIH HHS R01 GM121679
6 · The paper itself

Abstract

The process of tumor cell invasion and metastasis includes assembly of invadopodia, protrusions capable of degrading the extracellular matrix (ECM). The effect of cell cycle progression on invadopodia has not been elucidated. In this study, by using invadopodia and cell cycle fluorescent markers, we show in 2D and 3D cultures, as well as

Indexed as

G1 PhaseAnimalsCell LineCyclin-Dependent Kinase Inhibitor p27Extracellular MatrixGene Knockout TechniquesMatrix Metalloproteinase 14MicePhosphate-Binding ProteinsPodosomesS PhaseCdkn1b protein, mouseCyclin-Dependent Kinase Inhibitor p27Fish protein, mouseMatrix Metalloproteinase 14Mmp14 protein, mousePhosphate-Binding ProteinsCell cycleFUCCIG1Intravital imagingInvadopodiaInvasion

Identifiers

PMID31533971
PMCPMC6826011
OpenAlexW2974375523

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.