Evidence map›Paper›PMID 31546633›Full record

ArticleMolecules (Basel, Switzerland)2019

Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents.

Anastasia L Khandazhinskaya, Elena S Matyugina, Pavel N Solyev, Maggie Wilkinson, Karen W Buckheit, Robert W Buckheit, Larisa N Chernousova, Tatiana G Smirnova, Sofya N Andreevskaya, Khalid J Alzahrani and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anastasia L KhandazhinskayaEngelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia. khandazhinskaya@bk.ru.
Elena S MatyuginaEngelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia. matyugina@gmail.com.
Pavel N SolyevEngelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia. solyev@gmail.com.ORCID 0000-0002-5546-4975
Maggie WilkinsonImQuest BioSciences, 7340 Executive Way Suite R, Frederick, MD 21704, USA. mwilkinson@imquestbio.com.
Karen W BuckheitImQuest BioSciences, 7340 Executive Way Suite R, Frederick, MD 21704, USA. kbuckheit@imquestbio.com.
Robert W BuckheitImQuest BioSciences, 7340 Executive Way Suite R, Frederick, MD 21704, USA.
Larisa N ChernousovaCentral Tuberculosis Research Institute, 2 Yauzskaya Alley, Moscow 107564, Russia. lchernousova@mail.ru.
Tatiana G SmirnovaCentral Tuberculosis Research Institute, 2 Yauzskaya Alley, Moscow 107564, Russia. s_tatka@mail.ru.
Sofya N AndreevskayaCentral Tuberculosis Research Institute, 2 Yauzskaya Alley, Moscow 107564, Russia. andsofia@mail.ru.
Khalid J AlzahraniInstitute of Infection, Immunity and Inflammation, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK. Khalid-zh@hotmail.com.
Manal J NattoInstitute of Infection, Immunity and Inflammation, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK. Manal.Natto@glasgow.ac.uk.
Sergey N KochetkovEngelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia. kochet@eimb.ru.
Harry P de KoningInstitute of Infection, Immunity and Inflammation, University of Glasgow, Sir Graeme Davies Building, 120 University Place, Glasgow G12 8TA, UK. harry.de-koning@glasgow.ac.uk.ORCID 0000-0002-9963-1827
Katherine L Seley-RadtkeDepartment of Chemistry & Biochemistry, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. kseley@umbc.edu.ORCID 0000-0002-0154-3459

Funding

Government of Saudi Arabia S8306Russian Foundation for Basic Research 18-29-08010Taif University no number
6 · The paper itself

Abstract

Carbocyclic nucleosides have long played a role in antiviral, antiparasitic, and antibacterial therapies. Recent results from our laboratories from two structurally related scaffolds have shown promising activity against both

Indexed as

Anti-Bacterial AgentsAntiprotozoal AgentsMolecular StructureMycobacterium tuberculosisNucleosidesStructure-Activity RelationshipAnti-Bacterial AgentsAntiprotozoal AgentsNucleosidesantiparasiticcarbocyclicleishmanialmycobacterialnucleosidestuberculosis

Identifiers

PMID31546633
PMCPMC6804079

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.