Evidence map›Paper›PMID 31547438›Full record

Trial reportNutrients2019

Impact of Moderate Sodium Restriction and Hydrochlorothiazide on Iodine Excretion in Diabetic Kidney Disease: Data from a Randomized Cross-Over Trial.

S Heleen Binnenmars, Eva Corpeleijn, Arjan J Kwakernaak, Daan J Touw, Ido P Kema, Gozewijn D Laverman, Stephan J L Bakker, Gerjan Navis

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 3 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. The effect of sodium restriction on iodine prophylaxis: a review.Journal of endocrinological investigation · 2022
    Pooled it
  3. Altered dietary salt intake for people with chronic kidney disease.The Cochrane database of systematic reviews · 2021
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

S Heleen BinnenmarsDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. s.h.binnenmars@umcg.nl.
Eva CorpeleijnDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. e.corpeleijn@umcg.nl.
Arjan J KwakernaakDepartment of Internal Medicine, Division of Nephrology, Amsterdam University Medical Center, University of Amsterdam, 1100 DD Amsterdam, The Netherlands. a.j.kwakernaak@hotmail.com.
Daan J TouwDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. d.j.touw@umcg.nl.
Ido P KemaDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. i.p.kema@umcg.nl.
Gozewijn D LavermanDepartment of Internal Medicine, Division of Nephrology, ZGT Hospital, 7600 SZ Almelo/Hengelo, The Netherlands. g.laverman@zgt.nl.
Stephan J L BakkerDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. s.j.l.bakker@umcg.nl.ORCID 0000-0003-3356-6791
Gerjan NavisDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands. g.j.navis@umcg.nl.
University Medical Center Groningen · NLUniversity of Amsterdam · NLZiekenhuis Groep Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium restriction may potentially reduce iodine intake. This study aimed to determine the effect of sodium restriction (dietary counseling) on 24-h urinary iodine excretion. Diuretics provide an alternative to sodium restriction and are frequently added to sodium restriction, so the effects of hydrochlorothiazide (50 mg daily) and combined therapy were also studied. We performed a post-hoc analysis of a Dutch multi-center, randomized cross-over trial in 45 patients with diabetic kidney disease with a mean age of 65 ± 9 years, mean eGFR of 65 ± 27 mL/min/1.73 m

Indexed as

AgedCross-Over StudiesDiabetic NephropathiesDiet, Sodium-RestrictedFemaleHumansHydrochlorothiazideIodineMaleMiddle AgedSodiumSodium, DietaryHydrochlorothiazideIodineSodiumSodium, Dietary24-h urinary excretiondiabetic kidney diseaseiodinesodium

Identifiers

PMID31547438
PMCPMC6770176
OpenAlexW2972593364

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.