Evidence map›Paper›PMID 31558859›Full record

ReviewWorld journal of gastroenterology2019

Optimizing proton pump inhibitors in

Enzo Ierardi, Giuseppe Losurdo, Rosa Federica La Fortezza, Mariabeatrice Principi, Michele Barone, Alfredo Di Leo

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05664685 (Optimized Bismuth Quadruple Therapy vs Triple Standard Therapy for Helicobacter Pylori Eradication), which is not on this map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05664685 phase4completednot on this mapstarted 2022, after this paper: background citation

Optimized Bismuth Quadruple Therapy vs Triple Standard Therapy for Helicobacter Pylori Eradication: Clinical Efficacy Randomized Trial

TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2022 to 2024Enrolled127ConditionsHelicobacter Pylori InfectionArmsOptimized bismuth quadruple therapy, Control
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Different dose of new generation proton pump inhibitors for the treatment ofInternational journal of immunopathology and pharmacology
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Optimized sequential therapyWorld journal of gastroenterology · 2024
    Trial
  8. Trial
  9. Efficacy and Safety of Tegoprazan inPharmaceuticals (Basel, Switzerland) · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Dysregulated macrophage immunity inFrontiers in immunology · 2025
    Review
  16. Article
  17. Comparison of Tegoprazan- and Lansoprazole-Based Fourteen-Day Triple Therapies as First-Line Treatments forThe Korean journal of helicobacter and upper gastrointestinal research · 2024
    Article
  18. Article
  19. Article
  20. The prevalence and treatment outcomes ofJGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Enzo IerardiSection of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy. e.ierardi@virgilio.it.
Giuseppe LosurdoSection of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.
Rosa Federica La FortezzaSection of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.
Mariabeatrice PrincipiSection of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.
Michele BaroneSection of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.
Alfredo Di LeoSection of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari 70124, Italy.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The survival and replication cycle of

Indexed as

Anti-Bacterial AgentsDose-Response Relationship, DrugDrug Therapy, CombinationGastric MucosaHelicobacter InfectionsHelicobacter pyloriH(+)-K(+)-Exchanging ATPaseHumansHydrogen-Ion ConcentrationProton Pump InhibitorsTreatment OutcomeAnti-Bacterial AgentsH(+)-K(+)-Exchanging ATPaseProton Pump InhibitorsCytochrome P450EradicationHelicobacter pyloriOptimizationProton pump inhibitors

Identifiers

PMID31558859
PMCPMC6747288
OpenAlexW2972783296

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.