Evidence map›Paper›PMID 31560920›Full record

ArticleBehavioural brain research2020

Contribution of GABA

Tracie A Paine, Sara Chang, Rachel Poyle

Abstract read
In one paragraph

Article in Behavioural brain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. A new approach for cognitive impairment pattern in chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  5. Phenols and GABAFrontiers in pharmacology · 2024
    Review
  6. Article
  7. Article
  8. Effects of α5 GABACNS neuroscience & therapeutics · 2022
    Article
  9. Review
  10. GABAJournal, genetic engineering & biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tracie A PaineDepartment of Neuroscience, Oberlin College, Oberlin, OH, 44074, United States. Electronic address: tpaine@oberlin.edu.
Sara ChangDepartment of Neuroscience, Oberlin College, Oberlin, OH, 44074, United States.
Rachel PoyleDepartment of Neuroscience, Oberlin College, Oberlin, OH, 44074, United States.

Funding

Do 'schizophrenia-like' decreases in cortical GABA function impair cognition?R15MH098246 · NIMH · OBERLIN COLLEGE · PI PAINE, TRACIE ANN · 2012 to 2012
$268k
NIMH NIH HHS R15 MH098246
6 · The paper itself

Abstract

introductionGABA dysfunction is associated with a number of psychiatric conditions including schizophrenia, autism and depression. Blocking cortical GABA

methodsMale Sprague-Dawley rats were administered FG7142 (0.0-5.0 mg/kg; a non-selective GABA

resultsFG7142 decreased social interactions and impaired attention. MRK-016 impaired attention but did not affect social behavior. Neither L-655,708 nor L-838,417 significantly affected either social behavior or attention. DISCUSSION: Systemic reduction in GABA

Indexed as

Social BehaviorAnimalsAttentionBehavior, AnimalFluorobenzenesGABA-A Receptor AgonistsImidazolesIsoxazolesMaleRatsRats, Sprague-DawleyReceptors, GABA-ATriazinesTriazolesFluorobenzenesGABA-A Receptor AgonistsImidazolesIsoxazolesL 655,708L 838,417MRK 016Receptors, GABA-ATriazinesTriazolesAttentionFG7142GABAL-655,708L-838,417MRK-016Sociability

Identifiers

PMID31560920
PMCPMC6948928

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.